Fig 1: Effect of acetaminophen and nicorandil on hepatic bcl2 levels in mice. Mice were pretreated with nicorandil (100 mg/kg) for seven days then intoxicated with a single injection of APAP (500 mg/kg). Hepatic bcl2 levels were assessed. *, # significantly different from control and APAP-treated groups respectively (p < 0.05) using one-way ANOVA followed by the Tukey–Kramer multiple comparisons test. APAP, acetaminophen; bcl-2, Cell Leukemia-2
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