Anti-Fibroblast Activation Protein Alpha antibodies are used for the immunodetection of the protein encoded by the FAP gene. In humans, the canonical protein has a reported length of 760 amino acid residues and a mass of 87.7 kDa. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in adipose tissue. A member of the Peptidase S9B protein family, it is known to be involved with angiogenesis and cell adhesion. Post-translational modifications have been described, including N-glycosylation. Other names for this target antigen include FAPA, FAPalpha, SIMP, prolyl endopeptidase FAP, 170 kDa melanoma membrane-bound gelatinase, and DPPIV. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 180 citations in the literature describe the use of Fibroblast Activation Protein Alpha antibodies in research. Immunohistochemistry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.