Anti-MAPK8 antibodies are used in the immunodetection of the protein mitogen-activated protein kinase 8. In humans, the canonical protein has a reported length of 427 amino acid residues and a mass of 48.3 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 5 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the CMGC Ser/Thr protein kinase protein family, MAPK8 is known to be a protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Synonyms for this target antigen include JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c, and JNK. MAPK8 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 10000 citations in the literature describe the use of MAPK8 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.