Anti-mitofusin 2 antibodies are used in the immunodetection of the protein encoded by the MFN2 gene. In humans, the canonical protein has a reported length of 757 amino acid residues and a mass of 86.4 kDa. Its subcellular localization is in the mitochondria. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Dynamin/Fzo/YdjA protein family, it is known to be involved with the apoptotic pathway. Post-translational modifications have been described, including ubiquitination and phosphorylation. Other names for this target antigen include CMT2A2, CMT2A2A, CMT2A2B, CPRP1, HMSN6A, HSG, MARF, and CMT2A.