Mitofusin-2 (D2D10) Rabbit mAb from Cell Signaling Technology

Yes, the Mitofusin-2 (D2D10) Rabbit mAb has been shown to play a role in mitochondrial dynamics, particularly in the regulation of apoptosis. For instance, in studies, it was found that mitofusin expression, including MFN2, is crucial for maintaining mitochondrial integrity and preventing apoptosis in HIV-infected macrophages, as highlighted in the research by Campbell et al. (campbell2019).

Yes, the Mitofusin-2 antibody has been effectively utilized in Western blotting applications, as evidenced by its inclusion in multiple studies, including those examining mitochondrial function and dynamics in various cellular contexts, such as cardiac dysfunction and oxidative stress responses (du2024, guo2022).

The Mitofusin-2 antibody is reactive with several species, including human, mouse, rat, and non-human primates, making it suitable for immunocytochemistry applications across these organisms (9482s).

Yes, the Mitofusin-2 antibody has been associated with several critical cellular processes, including mitochondrial fusion and the regulation of mitochondrial bioenergetics. For example, studies have indicated that MFN2 is involved in maintaining mitochondrial function and preventing DNA damage under conditions of oxidative stress, as discussed in research by Cao et al. (cao2022).