Anti-CREB Binding Protein antibodies are used for the immunodetection of the protein encoded by the CREBBP gene. In humans, the canonical protein has a reported length of 2442 amino acid residues and a mass of 265.4 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is noted to be involved in the regulation of transcription. Post-translational modifications have been described, including sumoylation, acetylation and phosphorylation. The gene encoding this protein is implicated in Rubinstein-Taybi syndrome. Other names for this target antigen include KAT3A, MKHK1, RSTS, RSTS1, histone lysine acetyltransferase CREBBP, and CBP. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 230 citations in the literature describe the use of CREB Binding Protein antibodies in research. ELISA, Western Blot, Immunofluorescence, and Immunohistochemistry are common applications for these antibodies.