Anti-TNFRSF4 antibodies are used in the immunodetection of the protein TNF receptor superfamily member 4. In humans, the canonical protein has a reported length of 277 amino acid residues and a mass of 29.3 kDa. Its subcellular localization is in the membrane. It is notably expressed in the lymph node and tonsil. TNFRSF4 is a known receptor for TNFSF4/OX40L/GP34. Post-translational modifications have been described, including glycosylation. The TNFRSF4 marker can be used to identify Regulatory T Cells.* Synonyms for this target antigen include CD134, IMD16, OX40, TXGP1L, tumor necrosis factor receptor superfamily member 4, and ACT35. TNFRSF4 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4