Anti-CLTC antibodies are used in the immunodetection of the protein clathrin heavy chain. In humans, the canonical protein has a reported length of 1675 amino acid residues and a mass of 191.6 kDa. Its subcellular localization is in the membrane, cytoplasmic vesicles, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Clathrin heavy chain protein family, CLTC is known to be involved with autophagy pathways and cell division. Synonyms for this target antigen include CHC17, CLH-17, CLTCL2, Hc, MRD56, clathrin heavy chain 1, clathrin heavy chain on chromosome 17, and CHC. CLTC gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 320 citations in the literature describe the use of CLTC antibodies in research. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.