Anti-TIM-3 antibodies enable researchers to detect and measure the TIM-3 antigen in biological samples. This target is a reported synonym of the HAVCR2 gene, which encodes hepatitis A virus cellular receptor 2. This protein is known to function in adaptive immune responses and the cellular response to lipopolysaccharides, among other biological roles. The human version of TIM-3 has a canonical amino acid length of 301 residues and a protein mass of 33.4 kilodaltons, although 2 isoforms have been identified. It is reported to be localized in the cell membrane of cells and notably expressed in the rectum, lymph node, kidney, duodenum, and colon. TIM-3 is a member of the TIM protein family.