Anti-Fatty Acid Synthase antibodies are used for the immunodetection of the protein encoded by the FASN gene. In humans, the canonical protein has a reported length of 2511 amino acid residues and a mass of 273.4 kDa. Its subcellular localization is in the cytoplasm. It is ubiquitously expressed across many tissue types. It is noted to be involved in fatty acid metabolism and inflammatory response pathways. The fatty acid synthase marker can be used to characterize Adipocytes.* Other names for this target antigen include OA-519, SDR27X1, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, 3-oxoacyl-[acyl-carrier-protein] reductase, and FAS. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4