Anti-Fatty Acid Synthase antibody [N1], N-term GTX109833 from GeneTex

Product Specs
ItemAnti-Fatty Acid Synthase antibody [N1], N-term
CompanyGeneTex
Price $169.00Supplier Page
Catalog NumberGTX109833
ReactivityHuman, Mouse, Rat
ClonalityPolyclonal
FormatPBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300
ApplicationsWB, ICC/IF, IHC-P, IHC-Fr, IP
Quantity25 µl
Conjugate/TagUnconjugated
HostRabbit
ImmunogenRecombinant protein encompassing a sequence within the N-terminus region of human Fatty Acid Synthase. The exact sequence is proprietary
Concentration0.2mg/ml
IsotypeIgG
Antibody TypePrimary Antibodies
NCBI Full Gene Namefatty acid synthase
NCBI Gene Aliasesfatty acid synthase, FAS, OA-519, SDR27X1, OA-519, SDR27X1, FAS
PurityPurified by antigen-affinity chromatography
TargetFatty Acid Synthase
Research AreaMetabolism, Cardiovascular
Gene NameFASN
Molecular Weight273

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GeneTex

GeneTex, Inc. 2456 Alton Parkway

Irvine, California 92606

United States

Phone: 1-877-GeneTex (436-3839) or 949-553-1900
Fax: 949-309-2888

Company Profile

Website: http://www.genetex.com

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(3) FASN inhibition shows the potential for enhancing radiotherapy outcomes by targeting glycolysis, AKT, and ERK pathways in breast cancerInternational journal of radiation biologyJanuary 1, 2025Chen CI, Kuo DY, Chuang HY.

(4) NCI677397 targeting USP24-mediated induction of lipid peroxidation induces ferroptosis in drug-resistant cancer cellsMolecular oncologySeptember 1, 2024Wang SA, Wu YC, Yang FM, Hsu FL, Zhang K, Hung JJ.

(5) Senescent Endothelial Cells Sustain Their Senescence-Associated Secretory Phenotype (SASP) through Enhanced Fatty Acid OxidationAntioxidants (Basel, Switzerland)November 2, 2023Giuliani A, Giudetti AM, Vergara D, Del Coco L, Ramini D, Caccese S, Sbriscia M, Graciotti L, Fulgenzi G, Tiano L, et al.Supplementary Materials. The primary antibodies used were anti-CPT1B (1:900, ab134988, Abcam, UK), FASN (1:1000 GTX109833, GeneTex, Irvine, CA, USA), p16/INK4a (1:200; sc-377,412, Santa Cruz Biotechnology, Dallas, TX, USA),

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(7) Dual-tracer positron emission tomography/computed tomography as an imaging probe of de novo lipogenesis in preclinical models of hepatocellular carcinomaFrontiers in medicineJanuary 1, 2022Tsao CH, Jhou RH, Ke CC, Chang CW, Chang CW, Yang BH, Huang WS, Shih BF, Liu RS.proteins on the PVDF membrane were reacted with primary antibodies, including anti-FASN (1:1,000, Genetex GTX109833), anti-ACSS2 (1:1,000, Genetex GTX30020), and anti-β-actin (1:1,000, Genetax GTX109639, as the internal

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(9) Loss of Acot12 contributes to NAFLD independent of lipolysis of adipose tissueExperimental & molecular medicineJuly 1, 2021Park S, Song J, Baek IJ, Jang KY, Han CY, Jun DW, Kim PK, Raught B, Jin EJ.sections were incubated with the following primary antibodies: ACOT12 (MBS273137, Mybiosource), FASN (GTX109833, GeneTex), SCD1 (ab19862, Abcam), PPARα (ab8934, Abcam), and HA-tag (3724, Cell Signaling). Positive

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(11) Allopurinol Prevents the Lipogenic Response Induced by an Acute Oral Fructose Challenge in Short-Term Fructose Fed RatsBiomoleculesOctober 11, 2019García-Arroyo FE, Monroy-Sánchez F, Muñoz-Jiménez I, Gonzaga G, Andrés-Hernando A, Zazueta C, Juárez-Rojas JG, Lanaspa MA, Johnson RJ, Sánchez-Lozada LG.CoA carboxilase (Genetex, GTX132081, 1:2500 dilution. Irvine, CA, USA), Fatty acid synthase (Genetex, GTX109833, 1:5000 dilution. Irvine, CA, USA) KHK (Genetex, GTX109591, 1:10,000. Irvine, CA, USA) Xanthine oxidase

(12) Clinical importance of FASN in relation to HIF-1α and SREBP-1c in gastric adenocarcinomaLife sciencesMay 1, 2019Ezzeddini R, Taghikhani M, Somi MH, Samadi N, Rasaee MJ.

(13) Fenofibrate induces human hepatoma Hep3B cells apoptosis and necroptosis through inhibition of thioesterase domain of fatty acid synthaseScientific reportsMarch 1, 2019You BJ, Hour MJ, Chen LY, Luo SC, Hsu PH, Lee HZ.

(14) Dietary supplementation with myo-inositol reduces hepatic triglyceride accumulation and expression of both fructolytic and lipogenic genes in rats fed a high-fructose dietNutrition research (New York, N.Y.)November 1, 2017Shimada M, Hibino M, Takeshita A.

(15) A novel small molecule liver X receptor transcriptional regulator, nagilactone B, suppresses atherosclerosis in apoE-deficient miceCardiovascular researchOctober 1, 2016Gui Y, Yao S, Yan H, Hu L, Yu C, Gao F, Xi C, Li H, Ye Y, Wang Y.

(16) Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathwayOncotargetApril 10, 2015Jhuang HJ, Hsu WH, Lin KT, Hsu SL, Wang FS, Chou CK, Lee KH, Tsou AP, Lai JM, Yeh SF, et al.