Fatty Acid Synthase (C20G5) Rabbit mAb 3180S from Cell Signaling Technology

Product Specs
ItemFatty Acid Synthase (C20G5) Rabbit mAb
CompanyCell Signaling Technology
Price $339.00 Inquire
Catalog Number3180S
Quantity100 µl
ApplicationsW, IP, IHC-P, IF-IC, FC-FP
ReactivityH, M, R
TargetFASN
HostRabbit
NCBI Gene AliasesFAS, OA-519, SDR27X1
ClonalityMonoclonal
NCBI Full Gene Namefatty acid synthase
Research AreaMetabolism
CloneC20G5
Molecular Weight273

Questions and Answers

Can this antibody be used to study fatty acid metabolism in cancer models?

Yes, the Fatty Acid Synthase (C20G5) Rabbit mAb has been utilized in studies examining lipid metabolism, particularly in cancer models. For instance, it was shown to interact with the Chikungunya virus RNA, highlighting its role in pro-viral activity through modulation of fatty acid synthesis, which is crucial in cancer metabolism ().

Is this antibody effective for immunohistochemistry applications?

The Fatty Acid Synthase (C20G5) Rabbit mAb has been demonstrated to work effectively in immunohistochemistry, as indicated by its use in various studies to analyze protein expression in tissue samples, including those related to metabolic pathways in cancer research ().

What species can this antibody detect, and is it suitable for human studies?

This antibody is reactive to multiple species, including humans, mice, and rats. Its application in human studies is supported by its use in research focusing on human cancer models, making it suitable for investigations involving human tissues ().

How has this antibody been utilized in the context of metabolic diseases?

The Fatty Acid Synthase (C20G5) Rabbit mAb has been referenced in studies investigating metabolic alterations in diseases such as pancreatic cancer, where it was used to assess fatty acid synthesis pathways that are often dysregulated in such conditions ().

Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Fatty acid scavenging enables cancer escape from KRAS inhibitionbioRxivApril 3, 2026Zihang Yuan, Bo Lin, Chunlan Wang, Yingying Miao, Da Zhang, Ziru Meng, Gangqi Wang, Andrew M Lowy, Michael Karin, Fei Yang, et al.Number,Company anti-pERK,4370,CST anti-ERK,4695,CST anti-pAKT,4060,CST anti-AKT,4685,CST anti-Actin,66009,Proteintech anti-CPT1A,15184-1-ap,Proteintech anti-ACSBG1,25104,ThermoFisher anti-TIM23,sc514463,Santa Cruz anti-SDHB,92649,CST anti-Ki67,Ab15580,Abcam anti-FASN,3180,CST anti-CD36,ET1701-24,HUABIO anti-FATP2,78771,CST anti-FATP3,12943-1-AP,Proteintech anti-FABP5,A27255,ABclonal anti-PI3Kγ,SC-166365,Santa Cruz

(2) METTL1-deficient mesenchymal stem cells protect against metabolic-associated fatty liver disease by increasing NAMPT secretionStem Cells Transl MedMarch 29, 2026Jiang Du, Yuxuan Zhang, Chiheng Wang, Yuyuan Wang, Hongen Zhang, Dunyong Zhao, Juntang Linfollowing proteins were obtained from Cell Signaling Technology: ACC-1 (#3676), SCD1 (#2794), FASN (#3180), p-AKT (#4060), and AKT (#9272). Additionally, a primary antibody to METTL1 (14994-1-AP), SIRT1 (13161-1-AP),

(3) Aerobic glycolysis drives differentiation of unilocular adipocytesJournal of Lipid ResearchMarch 17, 2026Alice Maestri, Min Cai, Ruby Schipper, Julia Backman, Alana Vannay, Anneli Olsson, Ewa Ehrenborg, Roland Nilsson, Carolina E. HagbergPA1-46128, Invitrogen), UCP1 (1:50, MAB6158, R&D Systems), PPARγ (1:50, 2435S, Cell Signaling), FAS (1:50, 3180, BioTechne), ATGL (1:50, 2138, Cell Signaling), Total OXPHOS cocktail (1:50, Ab110411, Abcam), TOMM20

(4) Age-related adiponectin resistance in human skeletal muscle dysfunction: in vivo and in vitro evidenceJournal of Translational MedicineMarch 5, 2026Surina Surina, Lucia Scisciola, Manuela Giovanna Basilicata, Ada Pesapane, Rosaria Anna Fontanella, Nunzia Balzano, Alberta Maria Maddalena Palazzo, Asad Zia, Giovanni Tortorella, Zeeshan Ulfat, et al.milk/TBS-T for 1 h, then incubated overnight at 4 °C with primary antibodies, FAS (Cell signaling cat. #3180); PPAR-γ (Cell signaling cat. #2443); oxidative stress cocktail (Abcam, ab179843); SOD2 (Abcam, ab13533),

(5) Apigenin Suppresses Bladder Cancer via the SIRT6-NCOA2-PPARα AxisInternational Journal of Biological SciencesFebruary 26, 2026Ying Liu, Zhen-Duo Shi, Yun-Fei Wei, Si-Yuan Jiang, Harsh Patel, Qian-Zi Liu, Yang Dong, Yi-Fang Liu, Lin Hao, Shan Gao, et al.overnight at 4 °C with primary antibodies diluted in PBS: CPT1A (CST, USA, 12252), FASN (CST, USA, 3180). HRP-conjugated anti-rabbit secondary antibody (Abcam, UK, ab205718) was applied for 1 h at 37°C. Staining

(6) Postbiotic Metabolites of Proanthocyanidins Reduce Adipogenesis In Vitro by Suppressing De Novo LipogenesisMoleculesFebruary 17, 2026Wasitha P. D. W. Thilakarathna, Madumani Amararathna, H. P. Vasantha Rupasingheanti-mouse secondary antibody (7076P2), anti-rabbit secondary antibody (7074S), fatty acid synthase (FAS, 3180S), peroxisome proliferator-activated receptor-γ (PPAR-γ, 2443S), and β-actin (12620S) were purchased

(7) FASN-mediated metabolic reprogramming drives CD4+ T cell hyperactivation in Sjögren’s syndrome via fatty acid oxidation-dependent oxidative phosphorylationArthritis Research & TherapyFebruary 13, 2026Lei Ye, Xijun Wang, Junhao Yin, Huan Shi, Jiayao Fu, Baoli Wang, Lingyan Zhengincluding COXIV (ab16056, Abcam, UK), ATP5A (ab176569, Abcam, UK), NDUFB8 (ab192878, Abcam, UK), FASN (3180, CST, USA) and β-Tublin (HRP-66240, Proteintech, China) (all diluted 1:1000). After gradual rewarming,

(8) FASN Inhibition Enhances the Efficacy of Chemotherapy in Colorectal Cancer by Inhibiting the DNA Damage ResponseCancer ResearchFebruary 9, 2026Moumita Banerjee, Yekaterina Y. Zaytseva, Ellen M. Reusch, Dana L. Napier, Sumati Hasani, Piotr Rychahou, Tadahide Izumi, Dennis A. Cheek, Jing Li, Robert M. Flight, et al.PARP (#9541; RRID:AB_331426), malonyl lysine (Malonyl-Lys) multiMab (#14942; RRID:2687627), FASN (#3180; RRID:AB_2100796), acetylated-Lys (Acetyl-Lys) (#9441; RRID:AB_331805), ATM (#2873; RRID:AB_2062659),

(9) Quercus infectoria gall extract modulates adipocyte differentiation and lipid metabolism through dual regulation of adipogenesis and lipolysis in 3T3-L1 adipocytesAnim Cells Syst (Seoul)February 9, 2026Chanawee Jakkawanpitak, Suttiwan Wunnoo, Decha Sermwittayawong, Phanthipha Runsaeng, Thanaporn Amnuaikit, Supayang Piyawan VoravuthikunchaiC/EBPα (D56F10) XP® Rabbit mAb (#8178), PPARγ (81B8) Rabbit mAb (#2443), Fatty Acid Synthase (FAS) (C20G5) Rabbit mAb (#3180), and Phospho-HSL (Ser660) Rabbit mAb (#45804), all purchased from Cell Signaling Technology (Danvers,

(10) Bile acids regulate lipid metabolism through selective actions on fatty acid absorptionCell MetabolismFebruary 3, 2026Alvin P. Chan, Kelsey E. Jarrett, Rochelle W. Lai, Madelaine C. Brearley-Sholto, Angela S. Cheng, Maria O. Taveras, Anne M. Iwata, Michelle E. Steel, Andrew Lau, Emily C. Whang, et al.,Cell Signaling Technology,Cat#3676S; RRID: AV_2219397 Rabbit monoclonal anti-FASN,Cell Signaling Technology,Cat#3180S; RRID: AB_2100796 Rabbit monoclonal anti-SCD1,Cell Signaling Technology,Cat#2794S; RRID: AB_2183099 Donkey

(11) High glucose diet induces hepatic iron overload contributing to metabolic dysfunctioniScienceJanuary 16, 2026Amanda Caceres, Nathaniel H.O. Harder, Jacob P. Padilla, Samuel E. Janisse, Austin M. Cole, Sonia E. Roedersheimer, Marie C. HeffernRESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, FAS (rabbit mAb),Cell Signaling Technology,Cat# 3180S; RRID:AB_2100793 GLUT2 (rabbit pAb),EMD Millipore,Cat# 07-1402-I; RRID:AB_11214034 SREBP-1 (mouse

(12) Tofogliflozin attenuates liver steatosis and fibrosis in non-diabetic non-alcoholic steatohepatitis miceBMC GastroenterologyJanuary 15, 2026Yoshinori Ozono, Hiroshi Kawakami, Hiroshi Hatada, Naomi Uchiyama, Souichiro Ogawa, Keisuke Uchida, Hotaka Tamura, Yuri Komaki, Kenichi Nakamura, Hisayoshi Iwakiri, et al.Cell Signaling Technology), carnitine palmitoyltransferase 1a (CPT1a) (ab234111, Abcam), fatty acid synthase (FASN) (#3180, Cell Signaling Technology), fatty acid transport protein 2 (FATP2) (#78771, Cell Signaling Technology),

(13) METTL3 abrogation promotes glioma progression through regulating the ISG15-FASN axis-mediated lipid metabolism in macrophagesNature CommunicationsJanuary 8, 2026Huilong Yin, Xiaoyi Yu, Chenglong Hu, Yuhang Yang, Mengke Wang, Yating Xing, Baile Zuo, Chenxing Zhang, Weilong Yang, Yitong Li, et al.the indicated antibodies. The primary antibody information is as follows: rabbit anti-FASN (1:1000, 3180S, Cell Signaling Technology), rabbit anti-ACLY (1:1000, 4332S, Cell Signaling Technology), rabbit anti-Phospho-ACLY

(14) Bioactive compounds from Sargassum horneri attenuates inflammation and obesity regulating by Nrf2/HO-1 and AMPK signaling pathwaysSci RepDecember 10, 2025Ramakrishna Chilakala, Hyeon Jeong Moon, Min Ju Kim, Kang Ho Ko, Jong Won Han, Min Seouk Jung, Sun Hee Cheongsecondary antibodies for Western blotting analysis. The primary antibodies SREBP-1 (#ab28481), FAS (#3180), ACC (# 3662), AMPK (#2532) and p-AMPK (#2535) protein expressions was performed on 100 μg of liver

(15) An ATF3 Inducer Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease Through the AMPK and PKA PathwaysInt J Mol SciDecember 9, 2025Ching-Feng Cheng, Ruey-Bing Yang, Wen-Ting Chen, Jia-Fang Chung, Hui-Chen KuCambridge, UK), ChREBP (#81958, Abcam), C/EBPβ (sc-7962, Santa Cruz, Dallas, TX, USA), fatty acid synthase (#3180, Cell Signaling Technology), SREBP1 (14088-1-AP, Proteintech, Rosemont, IL, USA), ATGL (#2138, Cell Signaling Technology

(16) Ei24 deficiency in brown adipocytes induces severe hypothermia under cold stress independent of UCP1 activityNat CommunDecember 1, 2025Su Bin Lee, Bui Thanh Thu, Tae Wook Nam, Yaechan Song, Jae Hoon Lee, Yangsik Jeong, Han-Woong LeeSanta Cruz Biotechnology), PLIN1 (#9349, Cell Signaling Technology), ACC1 (#3676, Cell Signaling Technology), FASN (#3180, Cell Signaling Technology), β-actin (sc-47778, Santa Cruz Biotechnology), PGC1α, (ab191838, Abcam;

(17) RNF186 controls glucose metabolism in metabolic dysfunction-associated fatty liver diseaseCell & bioscienceNovember 28, 2025Du J, Du Q, Zhang Y, Gao J, Wang C, Kou B, Jiang Y, Zhao D, Lin J.Cell Signaling Technology: AKT (#4691), p-AKT (Ser473) (#4060), p-GSK3β (#9322), GSK3β (#12456), Fasn (#3180), GCK (#3782), SCD1 (#2794), IRS-1 (#2382), p-IRS-1 (#2388), PI3K (#4292), p-PI3K (#4288), FoxO1 (#2880),

(18) Revealing the mechanism of Ganoderma lucidum insoluble dietary fiber alleviating NAFLD through transcriptomics and metabolomicsnpj Science of FoodNovember 17, 2025Siqi Wang, Baitong Liu, Yunxia Ma, Guochuan Jiang, Xuejun Liu, Hongrui Sundetection were purchased from Servicebio Biotechnology Co., Ltd. (Wuhan, China) The FAS antibody (C20G5, #3180) was purchased from Cell Signaling Technology, Inc.(USA).All other chemical reagents used in this study

(19) Development of a diagnostic model for MASLD and identification of daidzein as the potential drug using bioinformatics analysis and experimentsFrontiers in ImmunologyOctober 22, 2025Tao Wang, Hao Zhang, Kaixia Wang, Chunxue Liu, Nan Kong, Luocheng Zhou, Lihong Qu,Cell Signaling Technology; 2443S PPARD,Rabbit,Proteintech; 28053-1-AP FASN,Rabbit,Cell Signaling Technology; 3180S SCD1,Rabbit,Cell Signaling Technology; 2794 CPT1A,Rabbit,Cell Signaling Technology; 12252 CD36,Rabbit,Cell Signaling Technology

(20) K(ir)5.1-modulated potassium flux stimulates an anabolic kidney phenotypeiScienceOctober 17, 2025Wu A, Inoue MK, Zhang Y, Hasenour CM, Arroyo JP, Bock F, Yu A, Ferdaus MZ, Blackwell Y, Lazarenko RM, et al.RESOURCE,SOURCE,IDENTIFIER Antibodies,Antibodies,Antibodies ,, PEPCK,Cayman,10004943 PK,R&D,AF8519 FAS,Cell Signaling,3180 ACLY,Cell Signaling,13390 GLS1,Cell Signaling,56750 PDH,Cell Signaling,3205 pPDHa-S293,Cell Signaling,37115 PFK,Cell Signaling

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9/12/2016Very Nice FASN-Antibody Franz RicklefsThis is a very good FASN antibody. Just follow the instructions of the manufacturer. It gives you multiple bands but these are the different forms of FASN. I am interested in all different kinds of ... Read Review

Fatty Acid Synthase (C20G5) Rabbit mAb

Fatty Acid Synthase (C20G5) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Fatty Acid Synthase (C20G5) Rabbit mAb from Cell Signaling Technology

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