Anti-CXCR3 antibodies are essential reagents in flow cytometry for detecting the target protein, C-X-C motif chemokine receptor 3. CXCR3 regulates leukocyte trafficking by binding to chemokines, inducing integrin activation, cytoskeletal changes, and chemotactic migration. It has three unique isoforms (CXCR3-A, CXCR3-B and CXCR3-alt), each interacting with different C-X-C chemokines. CXCR3 is a G-protein-coupled receptor found on the cell membrane. It has been used as a phenotypic marker for NK T cells, T cells, NK cells, and eosinophils. Examine the supplier's provided validation data when comparing CXCR3 antibodies for flow cytometry. Also look for application-specific recommendations, such as dilutions, protocols, sample types, and other helpful usage notes.