Biolegend
PE anti-mouse CD183 (CXCR3) Antibody
155904
S18001A
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Antibodies are produced by plasma cells (PC) that are terminally differentiated B cells and play crucial roles in host protection against infections but are considered to mediate autoimmunity in patients with rheumatic diseases, such as systemic lupus (SLE) or rheumatoid arthritis (RA). Our research aims at understanding the biology of antibody secreting cells (ASC) and B cells in health and disease. Here, we aimed at staining CXCR3 in plasma cells.
Flow Cytometry
B6 mouse spleen
surface staining with CXCR3 PE (1/200), 20 min at 4C
Fc block (2.4G2 clone)
N/A
Flow cytometer
We observed that around 40% of the plasma cells (CD138hi) express CXCR3.
Accessible and high quality
Antibody has great signal, highly recommended