Kinases

Kinases are a class of enzymes that catalyze the transfer of phosphate groups, generally from high-energy molecules such as ATP to specific substrates. These enzymes play an important role in many metabolic pathways, especially in signal transduction, and can be broadly classified based on the groups they act on, such as proteins, carbohydrates, and lipids. Protein kinases phosphorylate proteins on serine, threonine, tyrosine, or histidine amino acid residues. Examples include MAP kinases, CDKs, and JAKs. Lipid kinases include phosphatidylinositol kinases like PI3 and PI3K. Carbohydrate kinases such as hexokinase and phosphofructokinase are involved in energy generation pathways. Other notable kinases include pyruvate kinase, which converts phosphoenolpyruvate to pyruvate, and creatine kinase, which is used as an indicator of tissue damage. Visit the supplier page for more product information, including details on enzyme activity.