The Biocompare Inhibitor Search Tool lets researchers browse thousands of compounds by searching by inhibitor name or by its target enzyme. Simply search by “Keywords” if you know the name of the inhibitor, or search by “Inhibitor Target” to enter the name of your protein of interest. Additionally, you may check the appropriate boxes to narrow down your search.
Caspase-10 is a cysteine protease that acts as an initiator in Fas-induced apoptosis and death receptor signaling. Caspase-10 mutation is associated with a rare genetic disorder called autoimmune lymphoproliferative syndrome (ALPS). Inhibitors to caspase-10 are primarily peptide-based and can act directly or often as an inhibitor of caspase activity upstream of caspase-10.