PDGFB ELISA kits are immunoassay tools for the measurement of the protein platelet derived growth factor subunit B, which is encoded by the PDGFB gene in humans. Functionally, this protein is reported to be a growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. The canonical protein structure is reported to have an amino acid length of 241 residues, a mass of 27.3 kDa, and is a member of the PDGF/VEGF growth factor protein family. It is known to be secreted and is notably expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. The protein has been noted to be post-translationally glycosylated. The PDGFB gene has been associated with the disease, Basal ganglia calcification. Other alias names for this target include PDGF-2, PDGF2, SIS, SSV, c-sis, PDGF subunit B, PDGF, B chain, and IBGC5.
The detection range for different PDGFB ELISA kits can vary, with some assays measuring target concentrations as low as 0.549 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.