IL6ST ELISA kits are immunoassay tools for the measurement of the protein interleukin 6 cytokine family signal transducer, which is encoded by the IL6ST gene in humans. Functionally, this protein is known to be involved in cytokine-mediated signaling pathways and the regulation of apoptosis. The canonical protein structure is reported to have an amino acid length of 918 residues, a mass of 103.5 kDa, and is a member of the Type I cytokine receptor protein family. It is known to be localized in the cell membrane and is secreted and is reported to be found in all the tissues and cell lines examined. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally N-glycosylated and phosphorylated. The IL6ST gene has been associated with the disease, Hyper-IgE recurrent infection syndrome. Other alias names for this target include CDW130, GP130, HIES4, HIES4A, HIES4B, IL-6RB, IMD94, and CD130.
The detection range for different IL6ST ELISA kits can vary, with some assays measuring target concentrations as low as 7.8 pg/mL and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.