Human Soluble gp130 Quantikine ELISA Kit DGP00 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman Soluble gp130 Quantikine ELISA Kit
CompanyR&D Systems, a Bio-Techne Brand
Price $680.00Supplier Page View Company Product Page
Catalog NumberDGP00
Quantity1 Kit
ApplicationsELISA
Detection Range0.13 - 8 ng/mL (Cell Culture Supernates), 0.25 - 16 ng/mL (Serum, Heparin Plasma, Citrate Plasma, EDTA Plasma)
ReactivityHuman
Sample TypeCell Culture Supernates (100 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Citrate Plasma (10 uL)
Sensitivity0.05 ng/mL (Cell Culture Supernates), 0.08 ng/mL (Serum, Heparin Plasma, Citrate Plasma, EDTA Plasma)
Detection Targetgp130
Assay Time4.5 hours or 5.5 hours
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
NCBI Full Gene Nameinterleukin 6 cytokine family signal transducer
NCBI Gene AliasesCD130, CDW130, GP130, HIES4, HIES4A, HIES4B, IL-6RB, IMD94, STWS2, sGP130

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Neuroinflammatory Signature of Post-Traumatic Confusional State: The Role of Cytokines in Moderate-to-Severe Traumatic Brain InjuryInternational Journal of Molecular SciencesSeptember 4, 2025Federica Piancone, Francesca La Rosa, Ambra Hernis, Ivana Marventano, Pietro Arcuri, Marco Rabuffetti, Jorge Navarro, Marina Saresella, Mario Clerici, Angela Comanduccirespectively; IL-6, and sgp130, Biotechne, Minneapolis, MN, USA; catalogue numbers n° SPCKB-PS-009384 and n° DGP00, respectively). Samples were read on a plate reader (Sunrise, Tecan, Mannedorf, Switzerland) and optical

(2) ABO blood group and COVID-19 severity: Associations with endothelial and adipocyte activation in critically ill patientsPloS oneJanuary 1, 2025Stukas S, Goshua G, Conway EM, Lee AYY, Hoiland RL, Sekhon MS, Y C Chen L.quantified using commercially available ELISAs from R&D Systems Inc. (Minneapolis, MN, USA; cat ID DR600 and DGP00) between June-Jul 2021. All cytokine analyses were done in the lab of Dr. Cheryl Wellington at the University

(3) IL-1 and TNF mediates IL-6 signaling at the maternal-fetal interface during intrauterine inflammationFrontiers in immunologyJanuary 1, 2024Presicce P, Roland C, Senthamaraikannan P, Cappelletti M, Hammons M, Miller LA, Jobe AH, Chougnet CA, DeFranco E, Kallapur SG.Rhesus macaque IL-6R ELISA kit (cat.# - ELK-IL6sR; RayBio, Norcross, GA) and Human Soluble gp130 Quantikine ELISA kit (cat.# - DGP00; R&D Systems, Minneapolis, MN) following manufacturer’s instructions. RNA Isolation, cDNA generation

(4) IL-6 Trans-Signaling Is Increased in Diabetes, Impacted by Glucolipotoxicity, and Associated With Liver Stiffness and Fibrosis in Fatty Liver DiseaseDiabetesDecember 1, 2023Aysim Gunes, Clémence Schmitt, Laurent Bilodeau, Catherine Huet, Assia Belblidia, Cindy Baldwin, Jeanne-Marie Giard, Laurent Biertho, Annie Lafortune, Christian Yves Couture, et al.were measured in conditioned media or plasma with ELISA, according to instructions (D6050, DR600, and DGP00, Human Quantikine ELISA kits; R&D Systems). Levels of secreted proteins were normalized to total cellular

(5) The Alzheimer's disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130Molecular neurodegenerationFebruary 21, 2023Müller SA, Shmueli MD, Feng X, Tüshaus J, Schumacher N, Clark R, Smith BE, Chi A, Rose-John S, Kennedy ME, et al.

(6) Circulating Microvesicles in Association with the NLRP3 Inflammasome in Coronary Thrombi from STEMI PatientsBiomedicinesSeptember 5, 2022Bratseth V, Nordeng J, Helseth R, Solheim S, Åkra S, Arnesen H, Chiva-Blanch G, Seljeflot I.

(7) Co-Occurrence of Interleukin-6 Receptor Asp358Ala Variant and High Plasma Levels of IL-6: An Evidence of IL-6 Trans-Signaling Activation in Deep Vein Thrombosis (DVT) PatientsBiomoleculesMay 10, 2022Salemi R, Gattuso G, Tomasello B, Lavoro A, Gaudio A, Libra M, Signorelli SS, Candido S.available kits (Human IL-6 HS-HS600C, Lot 314515; Human IL-6 Rα-DR600, Lot P226142; Human soluble gp130-DGP00, Lot P199893; Quantikine, R&D system, Minneapolis, MN, USA), according to the manufacturer’s protocol. The

(8) Tocilizumab is safe and tolerable and reduces C â€reactive protein concentrations in the plasma and cerebrospinal fluid of ALS patientsMuscle & NerveSeptember 1, 2021Carol Milligan, Nazem Atassi, Suma Babu, Richard J. Barohn, James B. Caress, Merit E. Cudkowicz, Armineuza Evora, Gregory A. Hawkins, Marlena Wosiskiâ€Kuhn, Eric A. Macklin, et al.(R&D Systems, USA, catalog # Q6000B, lot P186912; catalog # DR600, lots P185493 and P191955; catalog # DGP00, lot P161984, respectively) at Wake Forest School of Medicine. Details of methods are provided in the

(9) The Inflammasome Signaling Pathway Is Actively Regulated and Related to Myocardial Damage in Coronary Thrombi from Patients with STEMIMediators of inflammationJanuary 1, 2021Nordeng J, Schandiz H, Solheim S, Åkra S, Hoffman P, Roald B, Bendz B, Arnesen H, Helseth R, Seljeflot I.

(10) IL6 receptor³⁵⁸Ala variant and trans-signaling are disease modifiers in amyotrophic lateral sclerosisNeurology - Neuroimmunology NeuroinflammationNovember 1, 2019Marlena Wosiski-Kuhn et al.sIL6R, and sgp130 concentrations were measured with commercial kits (R&D Systems, Q6000B, DR600, and DGP00, respectively) according to the manufacturer’s instructions. ELISA plates were read on a Wallac plate

(11) Inhibitory Mechanism of the Outer Membrane Growth of Chronic Subdural HematomasJournal of neurotraumaJune 1, 2017Osuka K, Watanabe Y, Usuda N, Aoyama M, Iwami K, Takeuchi M, Watabe T, Takayasu M.

(12) Maternal country of origin, breast milk characteristics and potential influences on immunity in offspringClinical and experimental immunologyDecember 1, 2010Holmlund U, Amoudruz P, Johansson MA, Haileselassie Y, Ongoiba A, Kayentao K, Traoré B, Doumbo S, Schollin J, Doumbo O, et al.

(13) Serum soluble glycoprotein 130 concentration is inversely related to insulin sensitivity in women with polycystic ovary syndromeDiabetesApril 1, 2010Nikolajuk A, Kowalska I, Karczewska-Kupczewska M, Adamska A, Otziomek E, Wolczynski S, Kinalska I, Gorska M, Straczkowski M.

(14) Soluble and membrane levels of molecules involved in the interaction between clonal plasma cells and the immunological microenvironment in multiple myeloma and their association with the characteristics of the diseaseInternational journal of cancerJanuary 15, 2009Perez-Andres M, Almeida J, Martin-Ayuso M, De Las Heras N, Moro MJ, Martin-Nuñez G, Galende J, Cuello R, Abuín I, Moreno I, et al.

(15) Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritisArthritis and rheumatismMay 1, 2006Richards PJ, Nowell MA, Horiuchi S, McLoughlin RM, Fielding CA, Grau S, Yamamoto N, Ehrmann M, Rose-John S, Williams AS, et al.

(16) Circulating interleukin-6 family cytokines and their receptors in patients with congestive heart failureHeart and vesselsSeptember 1, 2004Hirota H, Izumi M, Hamaguchi T, Sugiyama S, Murakami E, Kunisada K, Fujio Y, Oshima Y, Nakaoka Y, Yamauchi-Takihara K.

(17) Arenavirus-mediated liver pathology: acute lymphocytic choriomeningitis virus infection of rhesus macaques is characterized by high-level interleukin-6 expression and hepatocyte proliferationJournal of virologyFebruary 1, 2003Lukashevich IS, Tikhonov I, Rodas JD, Zapata JC, Yang Y, Djavani M, Salvato MS.

(18) Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cellsExperimental cell researchOctober 15, 2002Erices A, Conget P, Rojas C, Minguell JJ.

(19) Discriminant power of combined cerebrospinal fluid tau protein and of the soluble interleukin-6 receptor complex in the diagnosis of Alzheimer's diseaseBrain researchMarch 27, 1999Hampel H, Teipel SJ, Padberg F, Haslinger A, Riemenschneider M, Schwarz MJ, Kötter HU, Scheloske M, Buch K, Stübner S, et al.

(20) Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression: no alteration of soluble gp130Neuroscience lettersJanuary 15, 1999Stübner S, Schön T, Padberg F, Teipel SJ, Schwarz MJ, Haslinger A, Buch K, Dukoff R, Lasser R, Müller N, et al.

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