Human sgp130 DuoSet ELISA DY228 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemHuman sgp130 DuoSet ELISA
CompanyR&D Systems, a Bio-Techne Brand
Price $890.00Supplier Page View Company Product Page
Catalog NumberDY228
NCBI Full Gene Nameinterleukin 6 cytokine family signal transducer
NCBI Gene AliasesCD130, CDW130, GP130, HIES4, HIES4A, HIES4B, IL-6RB, IMD94, STWS2, sGP130
StorageStore the unopened product at 2 - 8 °C. Do not use past expiration date
Detection Targetgp130
ReactivityHuman
Detection Range156.00 - 10000 pg/mL
ApplicationsELISA
Quantity1 Kit (for 15 Plates)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Injection Drug Use Alters Plasma Regulation of the B Cell ResponseCellsJune 10, 2024Sanghita Sarkar, Dave D. Hill, Alexander F. Rosenberg, Ellen F. Eaton, Olaf Kutsch, James J. Kobieplasma was measured using the Human LBP (R&D Systems, DY870-05) and Human sgp130 ELISA (R&D Systems, DY228) kits respectively. 2.4. In Vitro Lymphocyte Proliferation Assays PBMCs were thawed and centrifuged

(2) Targeting IL-6 trans-signalling by sgp130Fc attenuates severity in SARS-CoV-2 -infected mice and reduces endotheliopathyEBioMedicineMay 1, 2024Rodríguez-Hernández MÁ, Baena-Bustos M, Carneros D, Zurita-Palomo C, Muñoz-Pinillos P, Millán J, Padillo FJ, Smerdou C, von Kobbe C, Rose-John S, et al.from human cultured cells were performed according to the manufacturer's instructions: sgp130 (DuoSet DY228), CCL2/MCP-1 (DuoSet DY279-05), ICAM-1/CD54 (DuoSet DY720-05), from R&D Systems (Minneapolis, MN, USA);

(3) Associations between serum estradiol and IL-6/sIL-6R/sgp130 complex in female patients with major depressive disorderBMC PsychiatryOctober 12, 2023Ting Sun, Qian Chen, Junchi Mei, Yan Liwere detected by enzyme-linked immunosorbent assay (ELISA) kits (Quantikine DY206, DY227, DY008, and DY228; R&D Systems, USA). The serum levels of IL-6 were measured without diluting the sample, but the serum

(4) Interleukin 6 trans-signalling and the risk of future cardiovascular events in men and womenOpen HeartOctober 11, 2021Yasmin Miri, Karin Leander, Per Eriksson, Bruna Gigante, Louise ZieglerDiscovery Systems Cytokine Assay (Gaithersburg, MD, USA) and sgp130 with an assay development kit (#DY228) from R&D Systems (R&D Systems, Minneapolis, MN, USA). All experiments were performed according to the

(5) Preeclampsia Status Controls Interleukin-6 and Soluble IL-6 Receptor Release from Neutrophils and Endothelial Cells: Relevance to Increased Inflammatory ResponsesPathophysiologyApril 8, 2021Yuping Wang, Yang Gu, J. Steven Alexander, David F. Lewisenzyme-linked immunosorbent assay (ELISA). DuoSet ELISA development kits of IL-6 (DY206), sIL-6R (DY227), and sgp130 (DY228) were purchased from R&D systems (Minneapolis, MN, USA). ELISA assay was performed according to the

(6) Transgenic inhibition of interleukin-6 trans-signaling does not prevent skeletal pathologies in mucolipidosis type II miceScientific reportsFebruary 11, 2021Westermann LM, Baranowsky A, Di Lorenzo G, Danyukova T, Soul J, Schwartz JM, Hendrickx G, Amling M, Rose-John S, Garbers C, et al.

(7) Expression of Interleukin 6 signaling receptors in carotid atherosclerosisVascular MedicineFebruary 1, 2021Louise Ziegler, Jasmin Lundqvist, Kristian Dreij, HÃ¥kan WallÃ©n, Ulf de Faire, Gabrielle Paulsson-Berne, Ulf Hedin, Ljubica Matic, Bruna Gigantecytokine assay (Gaithersburg, MD, USA). Plasma levels of sgp130 were assessed using a developmental kit (#DY228) from R&D Systems (Minneapolis, MN, USA).8 All analyses were performed in accordance with the manufacturer’s

(8) Trans IL-6 signaling does not appear to play a role in renal scarring after urinary tract infectionJournal of pediatric urologyOctober 1, 2020Gupta S, Junquera GY, Nicassio L, Becknell B, Ching CB.

(9) IL-6 Trans-Signaling in the Brain Influences the Metabolic Phenotype of the 3xTg-AD Mouse Model of Alzheimer's DiseaseCellsJuly 2, 2020Escrig A, Molinero A, Méndez B, Giralt M, Comes G, Sanchis P, Fernández-Gayol O, Giménez-Llort L, Becker-Pauly C, Rose-John S, et al.

(10) Associations between the IL-6-neutralizing sIL-6R-sgp130 buffer system and coronary artery disease in postmenopausal womenAnnals of Translational MedicineMay 2, 2020Man Zhou, Wen Dai, Yan Cui, Huan Liu, Yan Lienzyme-linked immunosorbent assay (ELISA) kits that were specific for human antigens (Quantikine DY206, DY227, DY228, and DY008; R&D Systems, Minneapolis, MN, USA) (14). Serum samples were undiluted to measure IL-6 and

(11) Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE studyGenes & ImmunityApril 1, 2020Alice Bonomi, Fabrizio on behalf of the IMPROVE study group, Fabrizio Baldassarre, Damiano Baldassarre, Rona J. Strawbridge, Zahra Golabkesh, Bengt Sennblad, Andries J. Leander, Andries J. Giral, Philippe Humphries, et al.67 subjects. Serum levels of sgp130 were measured by the Human sgp130 DuoSet ELISA development kit (#DY228) provided by R&D Systems® (R&D systems Minneapolis, MN, USA) using a protocol previously reported [51]. Statistical

(12) IL-6 exhibits both cis- and trans-signaling in osteocytes and osteoblasts, but only trans-signaling promotes bone formation and osteoclastogenesisThe Journal of biological chemistryMay 10, 2019McGregor NE, Murat M, Elango J, Poulton IJ, Walker EC, Crimeen-Irwin B, Ho PWM, Gooi JH, Martin TJ, Sims NA.

(13) The effect of rosuvastatin on inflammation, matrix turnover and left ventricular remodeling in dilated cardiomyopathy: a randomized, controlled trialPloS oneJanuary 1, 2014Broch K, Askevold ET, Gjertsen E, Ueland T, Yndestad A, Godang K, Stueflotten W, Andreassen J, Svendsmark R, Smith HJ, et al.

(14) Elevated Maternal Soluble Gp130 and IL-6 Levels and Reduced Gp130 and SOCS-3 Expressions in Women Complicated With PreeclampsiaHypertensionFebruary 1, 2011Yuping Wang, David F. Lewis, Yang Gu, Shuang Zhao, Lynn J. Groomewere measured by ELISA. DuoSet ELISA development kits of IL-6 (DY206), sIL-6R (DY227), and sgp130 (DY228) were purchased from R&D Systems (Minneapolis, MN). The assay procedures followed the instructions of

(15) Altered interleukin-6 receptor, IL-6R and gp130, production and expression and decreased SOCS-3 expression in placentas from women with pre-eclampsiaPlacentaDecember 1, 2008Zhao S, Gu Y, Dong Q, Fan R, Wang Y.

(16) Suspension microarrays for the identification of the response patterns in hyperinflammatory diseasesMedical engineering & physicsOctober 1, 2008Hsu HY, Wittemann S, Schneider EM, Weiss M, Joos TO.

(17) Soluble gp130, an antagonist of IL-6 transsignaling, is elevated in uveitis aqueous humorInvestigative ophthalmology & visual scienceSeptember 1, 2008Simon D, Denniston AK, Tomlins PJ, Wallace GR, Rauz S, Salmon M, Murray PI, Curnow SJ.

(18) Transgenic blockade of interleukin 6 transsignaling abrogates inflammationBloodFebruary 1, 2008Rabe B, Chalaris A, May U, Waetzig GH, Seegert D, Williams AS, Jones SA, Rose-John S, Scheller J.

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gp130 ELISA

Human sgp130 DuoSet ELISA

Human sgp130 DuoSet ELISA from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Human sgp130 DuoSet ELISA from R&D Systems, a Bio-Techne Brand

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