The following aspartyl-tRNA synthetase 1 ELISA kits are useful research tools for the measurement of aspartyl-tRNA synthetase 1 in biological samples. In humans this protein is encoded by the DARS1 gene. This protein is known to catalyze the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. The canonical protein structure is reported to have an amino acid length of 501 residues, a mass of 57.1 kDa, and is a member of the Class-II aminoacyl-tRNA synthetase protein family. Its subcellular location is known to be in the cytoplasm. As many as 2 protein isoforms have been reported. The gene encoding this protein has been associated with the disease, Hypomyelination with brainstem and spinal cord involvement and leg spasticity. This protein may also be known as HBSL, aspRS, aspartate--tRNA ligase, cytoplasmic, aspartate tRNA ligase 1, cytoplasmic, aspartyl-tRNA synthetase, cytoplasmic, and DARS.
Some aspartyl-tRNA synthetase 1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.