The following Caspase 7 ELISA kits are useful research tools for the measurement of caspase 7 in biological samples. In humans this protein is encoded by the CASP7 gene. This protein is known to be a thiol protease involved in different programmed cell death processes, such as apoptosis, pyroptosis or granzyme-mediated programmed cell death, by proteolytically cleaving target proteins. The canonical protein structure is reported to have an amino acid length of 303 residues, a mass of 34.3 kDa, and is a member of the Peptidase C14A protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is reported to be highly expressed in the lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. As many as 4 protein isoforms have been reported. In certain instances, it is also post-translationally cleaved and phosphorylated. This protein may also be known as ICE-LAP3, LICE2, MCH3, ICE-like apoptotic protease 3, apoptotic protease MCH-3, and CMH-1.
Some Caspase 7 ELISA kits can detect targets at levels as low as 20 ng/L and as high as 150 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.