Fig 1: Effect of treatment with abemaciclib (Abe) and irradiation (IRR, 10 Gy) on the concentration of caspase-3 (A), caspase-6 (B), caspase-7 (C), caspase-8 (D), and caspase-9 (E) in the cell lysate of MCF-7 and MDA-MB-231 cell lines. Results are expressed as means ± SD of two independent experiments performed in triplicate. The statistical significance of the results was analyzed using a one-way ANOVA followed by Tukey’s multiple comparison test. (a) Significantly different from the untreated cells; (b) Significantly different from Abe at P < 0.05