Anti-YWHAZ antibodies are used in the immunodetection of the protein tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta. In humans, the canonical protein has a reported length of 245 amino acid residues and a mass of 27.7 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the 14-3-3 protein family, YWHAZ is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Synonyms for this target antigen include HEL-S-3, HEL-S-93, HEL4, KCIP-1, POPCHAS, YWHAD, 14-3-3 protein zeta/delta, and 14-3-3-zeta. YWHAZ gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 150 citations in the literature describe the use of YWHAZ antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.