Anti-CDC6 antibodies are used in the immunodetection of the protein cell division cycle 6. In humans, the canonical protein has a reported length of 560 amino acid residues and a mass of 62.7 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is notably widely expressed in many tissue types. A member of the CDC6/cdc18 protein family, Cdc6 is reported to be involved in initiation of DNA replication. Post-translational modifications have been described, including ubiquitination. The CDC6 gene has been associated with the disease, Meier-Gorlin syndrome. Synonyms for this target antigen include HsCDC18, HsCDC6, MGORS5, cell division control protein 6 homolog, CDC6 cell division cycle 6 homolog, and CDC18L. CDC6 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 130 citations in the literature describe the use of Cdc6 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.