Cdc6 (180.2) Antibody sc-9964 from Santa Cruz Biotechnology, Inc.

Product Specs
ItemCdc6 (180.2) Antibody
CompanySanta Cruz Biotechnology, Inc.
Price $316.00Supplier Page View Company Product Page
Catalog Numbersc-9964
NCBI Gene AliasesMGORS5, HsCDC6, HsCDC18, p62(cdc6), CDC18L
Antibody TypePrimary Antibodies
Clone180.2
ApplicationsWB, IP, IF, IHC(P)
Reactivitymouse, rat, human
Quantity200 µg/ml
FormatPurified
ClonalityMonoclonal
Hostmouse
Conjugate/TagUnconjugated
NCBI Full Gene Namecell division cycle 6
TargetCdc6
IsotypeIgG1

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Utility of Tumor Suppressor E2F Target Gene Promoter Elements to Drive Gene Expression Specifically in Cancer CellsCellsDecember 9, 2025Kenta Kurayoshi, Masakazu Tanaka, Rinka Nakajima, Yaxuan Zhou, Mashiro Shirasawa, Mariana Fikriyanti, Jun-Ichi Fujisawa, Ritsuko Iwanaga, Andrew P. Bradford, Keigo Araki, et al.antibodies used were anti-E2F3 (sc-878, Santa Cruz Biotechnology, Dallas, TX, USA, 1:300), anti-CDC6 (sc-9964, Santa Cruz, 1:500), anti-Cyclin A (sc-751, Santa Cruz, 1:500), anti-Adenovirus 5 E1a (M58; BD Biosciences

(2) DNA replication in primary hepatocytes without the six-subunit ORCeLifeApril 30, 2025Przanowska RK, Chen Y, Uchida TO, Shibata E, Hao X, Rueda IS, Jensen K, Przanowski P, Trimboli A, Shibata Y, et al.sc-374231); ORC5 (Boster Biological technology; A03676-1); ORC6 (Santa Cruz; sc-390490); CDC6 (Santa Cruz; sc-9964); MCM2 (Abcam; ab4461); MCM3 (Santa Cruz; sc-9850). Histology and analysis All formalin-fixed paraffin-embedded

(3) Reconstitution of human DNA licensing and the structural and functional analysis of key intermediatesNat CommunJanuary 8, 2025Jennifer N. Wells, Lucy V. Edwardes, Vera Leber, Shenaz Allyjaun, Matthew Peach, Joshua Tomkins, Antonia Kefala-Stavridi, Sarah V. Faull, Ricardo Aramayo, Carolina M. Pestana, et al.replicates. f Corresponding western blot analysis for hCDC6 (anti-hCDC6 mouse monoclonal, Santa Cruz, Cat# sc-9964) and hCDT1 (anti-hCDT1 mouse monoclonal, Santa Cruz, Cat# sc-365305) in the presence of hCDC6WT, hCDC6F375C

(4) A GATA2-CDC6 axis modulates androgen receptor blockade-induced senescence in prostate cancerJournal of experimental & clinical cancer research : CRJuly 29, 2023Mourkioti I, Polyzou A, Veroutis D, Theocharous G, Lagopati N, Gentile E, Stravokefalou V, Thanos DF, Havaki S, Kletsas D, et al.

(5) RRM2 and CDC6 are novel effectors of XBP1-mediated endocrine resistance and predictive markers of tamoxifen sensitivityBMC cancerMarch 30, 2023Barua D, Sultana A, Islam MN, Cox F, Gupta A, Gupta S.Biolegend, London, UK. Mouse ER-α Ab (Cat# sc-8002), Mouse RRM2 Ab (sc-376973), mouse CDC6 Ab (Cat# sc-9964) were purchased from Santa Cruz Biotechnology, Inc. (Bergheimer, Heidelberg, Germany). Anti-Rabbit (Cat#

(6) DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiationNature communicationsMarch 4, 2023Xu X, Chang CW, Li M, Omabe K, Le N, Chen YH, Liang F, Liu Y.(10252-1-AP, Proteintech, WB 1:1000), rabbit anti-CDC45 (A2047, Abclonal, WB 1:1000), mouse anti-CDC6 (sc-9964, Santa Cruz, WB 1:1000), rabbit anti-CDT1 (A16576, Abclonal, WB 1:1000), rabbit anti-Cyclin A (PA5-16519,

(7) Proteomic profiling reveals distinct phases to the restoration of chromatin following DNA replicationCell reportsJanuary 31, 2023Alvarez V, Bandau S, Jiang H, Rios-Szwed D, Hukelmann J, Garcia-Wilson E, Wiechens N, Griesser E, Ten Have S, Owen-Hughes T, et al.

(8) CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesisMolecular cellJanuary 5, 2023Ratnayeke N, Baris Y, Chung M, Yeeles JTP, Meyer T.

(9) Genetic instability from a single S phase after whole-genome duplicationNatureApril 1, 2022Gemble S, Wardenaar R, Keuper K, Srivastava N, Nano M, Macé AS, Tijhuis AE, Bernhard SV, Spierings DCJ, Simon A, et al.398024), mouse anti-E2F1 (1:2,000; Santa Cruz sc251, RRID AB 627476), mouse anti-CDC6 (1:500; Santa Cruz sc-9964, RRID AB 627236), rabbit anti-CDT1 (1:500; Cell Signaling 8064S, RRID AB 10896851), rabbit anti-treslin

(10) Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistanceActa pharmaceutica Sinica. BApril 1, 2022Wang H, Wang Q, Cai G, Duan Z, Nugent Z, Huang J, Zheng J, Borowsky AD, Li JJ, Liu P, et al.NRF2 [Santa cruz (H-300); sc-13032; 1:500]; KEAP1 (Santa cruz; sc-15246; 1:500); CDC6 (Santa cruz; sc-9964; 1:500); tubulin (Santa cruz; sc-5286; 1:2000); cleaved-PARP1 (Cell signaling; #9542; 1:1000); cleaved-caspase7

(11) Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell Cycle Exit after DNA DamageSSRN Electronic JournalApril 1, 2022Hendrika A. Segeren, Lotte van Rijnberk, Eva Moreno, Frank Riemers, Ruixue Yuan, Richard Wubbolts, Alain de Bruin, Bart WestendorpRESOURCE SOURCE IDENTIFIER Antibodies Mouse monoclonal anti-CDC6 Santa Cruz Biotechnology Cat # sc-9964; RRID: AB_627236 Rabbit monoclonal anti CHK1, phospho(Ser345) Cell Signaling Technology Cat# 2348;

(12) CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawalThe EMBO journalMarch 15, 2022Crozier L, Foy R, Mouery BL, Whitaker RH, Corno A, Spanos C, Ly T, Gowen Cook J, Saurin AT.1/1,000), rabbit anti‐MCM3 (A300‐192A, Bethyl Laboratories; 1/1,000), mouse anti‐CDC6 (Clone 180.2; sc‐9964, Santa Cruz; 1/500), mouse anti‐PCNA ((lone F‐2; sc‐25280, Santa Cruz; 1/1,000), mouse anti‐RB (554136,

(13) Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregationScience advancesJanuary 21, 2022Carvalhal S, Bader I, Rooimans MA, Oostra AB, Balk JA, Feichtinger RG, Beichler C, Speicher MR, van Hagen JM, Waisfisz Q, et al.anti–α-tubulin (1:2000; B-5-1-2, #sc-23948, Santa Cruz Biotechnology), and mouse anti-CDC6 (1:500; #sc-9964, Santa Cruz Biotechnology). Immunofluorescence Cells were seeded on 18-mm-diameter #1.5 coverslips

(14) A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganizationMolecular cellDecember 2, 2021Zampetidis CP, Galanos P, Angelopoulou A, Zhu Y, Polyzou A, Karamitros T, Kotsinas A, Lagopati N, Mourkioti I, Mirzazadeh R, et al.

(15) Chromatin loading of MCM hexamers is associated with di-/tri-methylation of histone H4K20 toward S phase entryNucleic acids researchDecember 2, 2021Hayashi-Takanaka Y, Hayashi Y, Hirano Y, Miyawaki-Kuwakado A, Ohkawa Y, Obuse C, Kimura H, Haraguchi T, Hiraoka Y.antibody (14C10; Cell Signaling Technology), anti-histone H3 antibody (1G1, (41)), anti-Cdc6 antibody (sc-9964; Santa Cruz Biotechnology), anti-Cdt1 (D10F11; Cell Signaling Technology), anti-Orc2 antibody (3G6;

(16) Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2eLifeDecember 1, 2021Enrico TP, Stallaert W, Wick ET, Ngoi P, Wang X, Rubin SM, Brown NG, Purvis JE, Emanuele MJ.anti-53BP1 [1:250, Abcam, ab36823], CDT1 [1:200, Cell Signaling Technology, 8064], CDC6 [1:100, Santa Cruz, sc-9964], HA [1:200, BioLegend, 901501]) in conventional blocking solution (cBS: 1% bovine serum albumin in

(17) UHRF1 promotes androgen receptor-regulated CDC6 transcription and anti-androgen receptor drug resistance in prostate cancer through KDM4C-Mediated chromatin modificationsCancer lettersNovember 1, 2021Gao Y, Liu Y, Liu Y, Peng Y, Yuan B, Fu Y, Qi X, Zhu Q, Cao T, Zhang S, et al.

(18) SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibitionNature communicationsOctober 1, 2021Ma J, Shi Q, Cui G, Sheng H, Botuyan MV, Zhou Y, Yan Y, He Y, Wang L, Wang Y, et al.1:500), MCM4 (Santa Cruz, Cat# sc-28317, 1:500), MCM7 (Santa Cruz, # sc-9966, 1:500), Cdc6 (Santa Cruz, # sc-9964, 1:500), ORC2 (Santa Cruz, # sc-32734, 1:500), HA.11 (Covance, #MMS-101R, 1:1000), BRD4 (Abcam, # ab1228874,

(19) A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cellsNature communicationsAugust 13, 2021Dagg RA, Zonderland G, Lombardi EP, Rossetti GG, Groelly FJ, Barroso S, Tacconi EMC, Wright B, Lockstone H, Aguilera A, et al.against BRCA1 (1:1000, Calbiochem, OP92), BRCA2 (1:1000, Calbiochem, OP95), CDC6 (1:1000, Santa Cruz, sc-9964), CHK1 [G-4] (1:1,00, Santa Cruz, SC-8408), Cyclin E [HE12] (1:1000, Santa Cruz, sc-247), FLAG [M2]

(20) PARP14 regulates cyclin D1 expression to promote cell-cycle progressionOncogeneJuly 1, 2021O'Connor MJ, Thakar T, Nicolae CM, Moldovan GL.(Cell Signaling, 9271), Cyclin A (Santa Cruz, sc-239), Cyclin B (Cell Signaling, 4138), Cdc6 (Santa Cruz, sc-9964), CDK4 (Cell Signaling Technology, 12790S), p27 (Santa Cruz, sc-56338), p21 (Cell Signaling Technology,

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12/8/2016Expression of CDC6 in Human Aortic Smooth Muscle Cells Arul ManiCell division cycle 6 (CDC6) is an essential regulator of DNA replication in eukaryotic cells. The important function of CDC6 is mainly in the assembly of prereplicative complexes at origins of ... Read Review

Cdc6 (180.2) Antibody

Cdc6 (180.2) Antibody from Santa Cruz Biotechnology, Inc.

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Santa Cruz Biotechnology, Inc.

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Cdc6 (180.2) Antibody from Santa Cruz Biotechnology, Inc.

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