Anti-MCM2 antibodies are used in the immunodetection of the protein minichromosome maintenance complex component 2. In humans, the canonical protein has a reported length of 904 amino acid residues and a mass of 101.9 kDa. Its subcellular localization is in the nucleus and chromosomes. It is notably expressed in many tissues, such as the appendix and bone marrow. A member of the MCM protein family, MCM2 is known to act as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. MCM2 is also used as a cellular marker for characterizing neuronal cells. Synonyms for this target antigen include CCNL1, CDCL1, D3S3194, DFNA70, MITOTIN, cdc19, DNA replication licensing factor MCM2, and BM28. MCM2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 300 citations in the literature describe the use of MCM2 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.