Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified A300-094A from Bethyl Laboratories, Inc.

Product Specs
ItemRabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified
CompanyBethyl Laboratories, Inc.
Price $461.00Supplier Page View Company Product Page
Catalog NumberA300-094A
Quantity100 µg
ApplicationsWB, IP, IHC
Concentration1000 µg/ml
Conjugate/TagUnconjugated
FormatWhole IgG
ReactivityHuman, Mouse
TargetMCM2, Phospho (S108)
HostRabbit
Antibody TypePrimary
NCBI Full Gene Nameminichromosome maintenance complex component 2
NCBI Gene AliasesCCNL1, BM28, cdc19, MITOTIN, CDCL1, D3S3194, DFNA70
ClonalityPolyclonal
IsotypeWhole IgG
Domain/Region/Terminussurrounding serine 108
Storage2 - 8°C

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Bethyl Laboratories, Inc.

P.O. Box 850

Montgomery, Texas 77356

United States

Phone: 1-800-338-9579
Fax: 1-866-597-6105

Email: orders@fortislife.com

Company Profile

Website: fortislife.com

(1) Lnk deficiency enhances translesion synthesis to alleviate replication stress and promote hematopoietic stem cell fitnessJ Clin InvestOctober 30, 2025Brijendra Singh, Md Akram Hossain, Xiao Hua Liang, Jeremie Fages, Carlo Salas Salinas, Roger A. Greenberg, Wei TongBethyl A300-245A), anti–pSer33 RPA2 (1:1,000; Bethyl A300-246A), anti–pSer108 MCM2 (1:1,000; Bethyl A300-094A), anti-MCM2 (1:1,000; Bethyl A301-191A), anti–pSer824 KAP1 (1:1,000; Bethyl A300-767A), anti-KAP1 (1:1,000;

(2) Lnk Deficiency Enhances Translesion Synthesis to Alleviate Replication Stress and Promote Hematopoietic Stem Cell FitnessJournal of Clinical InvestigationOctober 30, 2025Brijendra Singh, Md Akram Hossain, Xiao Hua Liang, Jeremie Fages, Carlo Salas Salinas, Roger A. Greenberg, Wei TongBethyl A300-245A), anti–pSer33 RPA2 (1:1,000; Bethyl A300-246A), anti–pSer108 MCM2 (1:1,000; Bethyl A300-094A), anti-MCM2 (1:1,000; Bethyl A301-191A), anti–pSer824 KAP1 (1:1,000; Bethyl A300-767A), anti-KAP1 (1:1,000;

(3) Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK InhibitorCancer Res CommunSeptember 1, 2023Lal S, Bhola NE, Sun BC, Chen Y, Huang T, Morton V, Chen KX, Xia S, Zhang H, Parikh NS, et al.Technology; CST9718), GAPDH (RRID:AB_2278695; R&D Systems; AF5718), pMCM2 (S108; RRID:AB_242513; Bethyl Lab; A300-094A), vinculin (RRID:AB_10559207; Cell Signaling Technology; CST4650), rabbit anti-goat IgG-HRP (R&D Systems;

(4) ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activityPLoS biologyJanuary 1, 2020Lovejoy CA, Takai K, Huh MS, Picketts DJ, de Lange T.TRF1 (de Lange #1449), MCM2 (Abcam, ab4461), Phospho-MCM2 S108 (Bethyl Laboratories, Montgomery, TX, A300-094A), γtubulin (MilliporeSigma, GTU-88), Actin (Santa Cruz Biotechnology, I-19), and HA.11 (BioLegend, San

(5) BRD4 facilitates replication stress-induced DNA damage responseOncogeneJuly 1, 2018Zhang J, Dulak AM, Hattersley MM, Willis BS, Nikkilä J, Wang A, Lau A, Reimer C, Zinda M, Fawell SE, et al.CDC7 (A302–504A), phospho-RPA32 S4/S8 (A300–245A), phospho-RPA32 S33 (A300246A), phospho-MCM2 S108 (A300–094A), phospho-MCM2 S53 (A300–756A), phospho-MCM2 S40/41 (A300–788A); from Millipore: phospho-Histone H2A.X

(6) Replication stress by Py-Im polyamides induces a non-canonical ATR-dependent checkpoint responseNucleic acids researchOctober 1, 2014Martínez TF, Phillips JW, Karanja KK, Polaczek P, Wang CM, Li BC, Campbell JL, Dervan PB.

(7) Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1Nucleic acids researchApril 1, 2014Tae-Hong Kang, Sun-Hee Leem

(8) A distinct role for recombination repair factors in an early cellular response to transcription-replication conflictsNucleic acids researchJanuary 1, 0001"Shao X, Joergensen AM, Howlett NG, Lisby M, Oestergaard VH."antibodies, respectively. For analysis of MCM2-Ser108P, rabbit anti-phospho MCM2 S108 antibody (1:1000, A300-094A, Bethyl), and anti-rabbit IgG conjugated to HRP (1:2000, P0217, Dako) were used as primary and secondary

(9) Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recoveryeLifeJanuary 1, 0001"Tonzi P, Yin Y, Lee CWT, Rothenberg E, Huang TT."(1:1000) Antibody Rabbit anti-POLI Bethyl Cat. #: A301-304A WB (1:5000) Antibody Rabbit anti-MCM2 Bethyl Cat. #: A300-094A WB (1:5000) Antibody Rabbit anti-MCM5 Bethyl Cat. #: A300-195A WB (1:5000) Antibody Rabbit antiHistone

(10) Improved detection of DNA replication fork-associated proteinsCell reportsJanuary 1, 0001"Rivard RS, Chang YC, Ragland RL, Thu YM, Kassab M, Mandal RS, Van Riper SK, Kulej K, Higgins L, Markowski TM, et al."anti-POLD1 antibody,Abcam,Cat# ab168827 Rabbit anti-phospho-MCM2 (S108) antibody,Bethyl Laboratory,Cat# A300-094A; RRID: AB_242513 Rabbit anti-phospho-MCM2 (S139) Antibody,Cell Signaling Technology,Cat# 8861; RRID:

(11) HERC2 Interacts with Claspin and regulates DNA origin firing and replication fork progressionCancer researchJanuary 1, 0001"Izawa N, Wu W, Sato K, Nishikawa H, Kato A, Boku N, Itoh F, Ohta T."

(12) Replication initiation complex formation in the absence of nuclear function in XenopusNucleic acids researchJanuary 1, 0001"Krasinska L, Fisher D."

(13) Plx1 is required for chromosomal DNA replication under stressful conditionsThe EMBO journalJanuary 1, 0001"Trenz K, Errico A, Costanzo V."

(14) Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinasesProceedings of the National Academy of Sciences of the United States of AmericaJanuary 1, 0001"Cortez D, Glick G, Elledge SJ."

(15) Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stressThe Journal of biological chemistryJanuary 1, 0001"Kemp MG, Akan Z, Yilmaz S, Grillo M, Smith-Roe SL, Kang TH, Cordeiro-Stone M, Kaufmann WK, Abraham RT, Sancar A, et al."

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Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified from Bethyl Laboratories, Inc.

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Bethyl Laboratories, Inc.

Citations (15)

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Rabbit anti-Phospho MCM2 (S108) Antibody, Affinity Purified from Bethyl Laboratories, Inc.

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