Anti-Cullin 1 antibodies are used for the immunodetection of the protein encoded by the CUL1 gene. In humans, the canonical protein has a reported length of 776 amino acid residues and a mass of 89.7 kDa. It is reported to be expressed in the lung fibroblasts. A member of the Cullin protein family, it is an important component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Post-translational modifications have been described, including ubiquitination. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 150 citations in the literature describe the use of Cullin 1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.