Anti-RPA2 antibodies are used in the immunodetection of the protein replication protein A2. In humans, the canonical protein has a reported length of 270 amino acid residues and a mass of 29.2 kDa. Its subcellular localization is in the nucleus. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Replication factor A protein 2 protein family, RPA2 is known to be involved with DNA replication and DNA repair. Post-translational modifications have been described, including ubiquitination and phosphorylation. Synonyms for this target antigen include RP-A p32, RP-A p34, RPA32, replication protein A 32 kDa subunit, RF-A protein 2, and REPA2. RPA2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 900 citations in the literature describe the use of RPA2 antibodies in research. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.