Anti-TP53BP1 antibodies are used in the immunodetection of the protein tumor protein p53 binding protein 1. In humans, the canonical protein has a reported length of 1972 amino acid residues and a mass of 213.6 kDa. Its subcellular localization is in the nucleus. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. TP53BP1 is known to be involved with DNA damage pathways and the regulation of transcription. Post-translational modifications have been described, including methylation and phosphorylation. Synonyms for this target antigen include TDRD30, p202, p53BP1, TP53-binding protein 1, p53-binding protein 1, and 53BP1. TP53BP1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 1400 citations in the literature describe the use of TP53BP1 antibodies in research. Western Blot is a widely used application for these antibodies. Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.