Anti-MAP2K1 antibodies are used in the immunodetection of the protein mitogen-activated protein kinase kinase 1. In humans, the canonical protein has a reported length of 393 amino acid residues and a mass of 43.4 kDa. Its subcellular localization is in the membrane, nucleus, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is found to be widely expressed, with extremely low levels in the brain. A member of the STE Ser/Thr protein kinase protein family, MAP2K1 is known to be involved with Bergmann glial cell differentiation and chemotaxis. Synonyms for this target antigen include MAPKK1, MEK1, MEL, MKK1, PRKMK1, and CFC3. MAP2K1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 3400 citations in the literature describe the use of Map2k1 antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.