Anti-CD63 antibodies are immunodetection reagents directed against the protein encoded by the gene, CD63 molecule in humans. These antibodies are widely used in numerous applications, including flow cytometry, immunohistochemistry, western blot, immunocytochemistry and peptide array. Orthologs for CD63 have also been reported in other species, including mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken. The canonical CD63 protein is 238 amino acids in length, 25.6 kDa in mass, and has a secreted, lysosomal, and membrane subcellular localization. It is a member of the Tetraspanin (TM4SF) protein family. It is reported to play roles in cell-matrix adhesion, cell migration, hemostasis, and the innate immune system. In terms of tissue expression, it is notably detected in platelets. Post-translational modifications have been described, notably palmitoylation. Synonyms for this protein include: LAMP-3; ME491; MLA1; OMA81H; TSPAN30; CD63 antigen; melanoma 1 antigen; granulophysin.