Easy and Solid CD10 Staining With Antibody From BD Biosciences

Pathology
UMass
Lab Technician

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
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Company:

BD Biosciences

Product Name:

BD™ CD10 APC

Catalog Number:

340922

Clone Number:

HI10a

Info:Supplier Page 

Browse Similar Products: Anti-CD10 Antibody Products

CD10 is positive on mature neutrophils, but can also be seen on immature B cells (hematogones). We needed a good CD10 antibody that would give a good signal without interfering with other antibodies and with minimal compensation required.

Experimental Design and Results Summary

Applications

Flow cytometry

Sample

Human WBC

Primary Incubation

15-20 minutes on ice

Blocking Agent

Not needed

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

Flow cytometer (with a red laser)

Results Summary

The anti-CD10 APC antibody stained the cells as expected (mature granulocytes). The signal is bright and distinct. No staining of monocytes was seen indicating lack of non-specific staining.

DOI or PMID #

N/A

Additional Notes

N/A

Image Gallery

Summary

The Good

Easy to optimize. Specific staining.

The Bad

Too expensive.

The Bottom Line

Overall, the staining worked OK and with minimum fuss. The positive cells are easy to resolve.

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