Pyruvate Dehydrogenase Assay Kits

Pyruvate Dehydrogenase assay kits include essential reagents to measure the protein abundance or activity of the pyruvate dehydrogenase (PDH) enzyme complex, which is essential in acetyl-CoA metabolism and the tricarboxylic acid (TCA) cycle. The PDH assay typically measures the conversion of pyruvate to acetyl-CoA and CO2. This reaction is coupled with the reduction of NAD+ to NADH, which can be monitored spectrophotometrically. Pyruvate Dehydrogenase assays can be used to study the role of PDH in different contexts, such as the metabolism of various cell types, mitochondrial dysfunction and metabolic disorders, and metabolic alterations in cancer. When choosing an enzyme assay kit, consider important specifications such as the enzyme activity detection range, recommended sample types, and the components included within the kit. Visit the supplier page for more details.