ddSEQTM Single-Cell ATAC-seq Kit from Bio-Rad

ddSEQTM Single-Cell ATAC-Seq Kit from Bio-Rad
Bio-Rad’s ddSEQ Single-Cell ATAC-Seq Library Prep Kit and Omnition Analysis Software enable genome-wide profiling of epigenomic landscape at the single-cell level with high number of reads per cell so you can better understand the mechanisms that drive how genes are regulated.

Features and Benefits

• Greater than 65% cell capture efficiency
• Adjustable cell throughput range of as few as 400 or more than 5,000 cells per sample
• Best sensitivity possible from the highest number of unique sequencing fragments that map to the nuclear genome, ATAC peaks, and transcription start sites
• A powerful and efficient informatics tool in a flexible pipeline
• Runs on the ddSEQ Single-Cell Isolator
• Works with nuclei or whole cells

Applications and Uses

• Answer deep questions about regulation of gene expression through interrogation of promoters, enhancers, or other regulatory elements
• Characterize relationships between cis-regulatory elements and non-coding genetic variation
• Validate scRNA-Seq studies as an orthogonal approach

Included Components

• ddSEQ Single-Cell ATAC-Seq Kit
• ddSEQ M Cartridges
• ddSEQ ATAC-Seq Reagent Box A
• ddSEQ ATAC-Seq Reagent Box B
• ddSEQ ATAC-Seq Index Kit with 24 Indexes