Fig 1: Determination of periaqueductal gray mGluR8 expression by Western blot immunoassay (A). As shown in the diagram (B), after injury, the expression level of mGluR8 decreased significantly compared to the sham group. DCPG treatment slightly changed the amount of these receptors in comparison with the siRNA group (n=3 independent rats/condition). SCI, spinal cord injury; DCPG, (S)-3,4-dicarboxyphenylglycine; mGluR8, metabotropic glutamate receptors subtype 8. a)Indicates a significant difference at p<0.001 in comparison to the sham group. b)Indicates a significant difference at p<0.001 in comparison to the SCI group.