SH-PTP2 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSH-PTP2 shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-36488-SH
Quantity20 µg
Vector Type (Standardized)Lentiviral
NCBI Gene AliasesBPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
NCBI Full Gene Nameprotein tyrosine phosphatase non-receptor type 11
Specieshuman
TypeshRNA Plasmid
RNA TypeshRNA Clones

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) 3-Formylchromone Counteracts STAT3 Signaling Pathway by Elevating SHP-2 Expression in Hepatocellular CarcinomaBiologyDecember 26, 2021Mohan CD, Yang MH, Rangappa S, Chinnathambi A, Alharbi SA, Alahmadi TA, Deivasigamani A, Hui KM, Sethi G, Rangappa KS, et al.

(2) Protein Tyrosine Phosphatase SHP2 Suppresses Host Innate Immunity against Influenza A Virus by Regulating EGFR-Mediated SignalingJournal of virologyFebruary 24, 2021Wang Q, Pan W, Wang S, Pan C, Ning H, Huang S, Chiu SH, Chen JL.

(3) SHP2 Nuclear/Cytoplasmic Trafficking in Granulosa Cells Is Essential for Oocyte Meiotic Resumption and MaturationFrontiers in cell and developmental biologyJanuary 1, 2020Idrees M, Kumar V, Joo MD, Ali N, Lee KW, Kong IK.

(4) SHP-2 is activated in response to force on E-cadherin and dephosphorylates vinculin Y822Journal of cell scienceDecember 14, 2018Campbell H, Heidema C, Pilarczyk DG, DeMali KA.

(5) PD-1 is required to maintain stem cell properties in human dental pulp stem cellsCell death and differentiationJuly 1, 2018Liu Y, Jing H, Kou X, Chen C, Liu D, Jin Y, Lu L, Shi S.

(6) Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interactionFASEB journal : official publication of the Federation of American Societies for Experimental BiologyNovember 1, 2017Yan M, Zhang X, Chen A, Gu W, Liu J, Ren X, Zhang J, Wu X, Place AT, Minshall RD, et al.

(7) Deletion of Shp2 in bronchial epithelial cells impairs IL-25 production in vitro, but has minor influence on asthmatic inflammation in vivoPloS oneJanuary 1, 2017Qiu Z, Zhou J, Liu F, Qin X, Dai Y, Ke Y, Chen Z, Li W, Ying S, Shen H.

(8) Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesisNature communicationsNovember 30, 2015Bunda S, Burrell K, Heir P, Zeng L, Alamsahebpour A, Kano Y, Raught B, Zhang ZY, Zadeh G, Ohh M.

(9) SHP2 positively regulates TGFβ1-induced epithelial-mesenchymal transition modulated by its novel interacting protein Hook1The Journal of biological chemistryDecember 5, 2014Li S, Wang L, Zhao Q, Liu Y, He L, Xu Q, Sun X, Teng L, Cheng H, Ke Y.

(10) Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatasesCancer lettersApril 1, 2014Lee JH, Chiang SY, Nam D, Chung WS, Lee J, Na YS, Sethi G, Ahn KS.

(11) A comprehensive analysis of GATA-1-regulated miRNAs reveals miR-23a to be a positive modulator of erythropoiesisNucleic acids researchApril 1, 2013Zhu Y, Wang D, Wang F, Li T, Dong L, Liu H, Ma Y, Jiang F, Yin H, Yan W, et al.cultures. The shRNA lentivirus plasmids specific to GATA-1 (sc-29330-SH, lenti_si_GATA-1) and SHP2 (sc-36488-SH, lenti_si_SHP2) were purchased from Santa Cruz Biotechnology and operated according to the manufacturer’s

(12) Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activityThe Journal of cell biologyFebruary 18, 2013Ahmed Z, Lin CC, Suen KM, Melo FA, Levitt JA, Suhling K, Ladbury JE.

(13) Modulation of fatty acid synthase degradation by concerted action of p38 MAP kinase, E3 ligase COP1, and SH2-tyrosine phosphatase Shp2The Journal of biological chemistryFebruary 8, 2013Yu J, Deng R, Zhu HH, Zhang SS, Zhu C, Montminy M, Davis R, Feng GS.

(14) SHP-2 phosphatase promotes cervical cancer cell proliferation through inhibiting interferon-β productionThe journal of obstetrics and gynaecology researchJanuary 1, 2013Meng F, Zhao X, Zhang S.

(15) Antagonism of VEGF-A-induced increase in vascular permeability by an integrin α3β1-Shp-1-cAMP/PKA pathwayBloodDecember 6, 2012Kim SH, Cho YR, Kim HJ, Oh JS, Ahn EK, Ko HJ, Hwang BJ, Lee SJ, Cho Y, Kim YK, et al.

(16) The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylationMolecular biology of the cellNovember 1, 2012Timmerman I, Hoogenboezem M, Bennett AM, Geerts D, Hordijk PL, van Buul JD.kinases, cells were pretreated for 30 min with 10 μM PP2 (Calbiochem) or SU6656 (Calbiochem). SHP2 siRNA (sc-36488-SH) was obtained from Santa Cruz Biotechnology. As a nonspecific control, a siRNA against a luciferase

(17) Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activityBloodNovember 26, 2009Nyström A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV.

(18) Dopamine regulates phosphorylation of VEGF receptor 2 by engaging Src-homology-2-domain-containing protein tyrosine phosphatase 2Journal of cell scienceSeptember 15, 2009Sinha S, Vohra PK, Bhattacharya R, Dutta S, Sinha S, Mukhopadhyay D.

(19) Tyrosine phosphatase SHP-2 is a regulator of p27(Kip1) tyrosine phosphorylationCell cycle (Georgetown, Tex.)December 15, 2008Tossidou I, Dangers M, Koch A, Brandt DT, Schiffer M, Kardinal C.

(20) Transforming signals resulting from sustained activation of the PDGFbeta receptor in mortal human fibroblastsJournal of cell scienceApril 15, 2008Petti LM, Ricciardi EC, Page HJ, Porter KA.

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