XBP-1 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemXBP-1 shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-38627-SH
Quantity20 µg
RNA TypeshRNA Clones
Vector Type (Standardized)Lentiviral
NCBI Gene AliasesTREB-5, TREB5, XBP-1, XBP2
NCBI Full Gene NameX-box binding protein 1
Specieshuman
TypeshRNA Plasmid

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cellsBiochemical and biophysical research communicationsJuly 12, 2022Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M.

(2) TXNIP Links Anticipatory Unfolded Protein Response to Estrogen Reprogramming Glucose Metabolism in Breast Cancer CellsEndocrinologyJanuary 1, 2022Wang Y, Chen S.

(3) IRE1α-XBP1 but not PERK inhibition exerts anti-tumor activity in osteosarcomaDiscov OncolNovember 30, 2021Sasa K, Saito T, Kurihara T, Hasegawa N, Sano K, Kubota D, Akaike K, Okubo T, Hayashi T, Takagi T, et al.

(4) Endoplasmic reticulum stress/XBP1 promotes airway mucin secretion under the influence of neutrophil elastaseInternational journal of molecular medicineMay 1, 2021Xu X, Li Q, Li L, Zeng M, Zhou X, Cheng Z.

(5) PGE2 Released by Pancreatic Cancer Cells Undergoing ER Stress Transfers the Stress to DCs Impairing Their Immune FunctionMolecular cancer therapeuticsMay 1, 2021Gilardini Montani MS, Benedetti R, Piconese S, Pulcinelli FM, Timperio AM, Romeo MA, Masuelli L, Mattei M, Bei R, D'Orazi G, et al.

(6) IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 ActivationBiomedicinesJanuary 27, 2021Gonnella R, Gilardini Montani MS, Guttieri L, Romeo MA, Santarelli R, Cirone M.

(7) A modified cholera toxin B subunit containing an ER retention motif enhances colon epithelial repair via an unfolded protein responseFASEB journal : official publication of the Federation of American Societies for Experimental BiologyDecember 1, 2019Royal JM, Oh YJ, Grey MJ, Lencer WI, Ronquillo N, Galandiuk S, Matoba N.

(8) Elevation of O-GlcNAc and GFAT expression by nicotine exposure promotes epithelial-mesenchymal transition and invasion in breast cancer cellsCell death & diseaseApril 24, 2019Zhang N, Zhu T, Yu K, Shi M, Wang X, Wang L, Huang T, Li W, Liu Y, Zhang J.

(9) IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signalingNature communicationsJanuary 24, 2019Sheng X, Nenseth HZ, Qu S, Kuzu OF, Frahnow T, Simon L, Greene S, Zeng Q, Fazli L, Rennie PS, et al.

(10) Upregulated long noncoding RNA LOC105375913 induces tubulointerstitial fibrosis in focal segmental glomerulosclerosisScientific reportsJanuary 24, 2019Han R, Hu S, Qin W, Shi J, Zeng C, Bao H, Liu Z.

(11) The long noncoding RNA LOC105374325 causes podocyte injury in individuals with focal segmental glomerulosclerosisThe Journal of biological chemistryDecember 28, 2018Hu S, Han R, Shi J, Zhu X, Qin W, Zeng C, Bao H, Liu Z.

(12) Role of X-Box Binding Protein-1 in Fructose-Induced De Novo Lipogenesis in HepG2 CellsChinese medical journalOctober 5, 2018Yu X, Ren LP, Wang C, Zhu YJ, Xing HY, Zhao J, Song GY.anti-FAS antibody, goat anti-mouse secondary antibody, XBP-1 short hairpin (sh) RNA plasmid (human, sc-38627-SH) and control shRNA plasmid-A (sc-108060; Santa Cruz Biotechnology, Santa Cruz, CA, USA); and PA and

(13) O-GlcNAc elevation through activation of the hexosamine biosynthetic pathway enhances cancer cell chemoresistanceCell death & diseaseMay 1, 2018Liu Y, Cao Y, Pan X, Shi M, Wu Q, Huang T, Jiang H, Li W, Zhang J.

(14) Regulation of Nrf2 by X Box-Binding Protein 1 in Retinal Pigment EpitheliumFrontiers in geneticsJanuary 1, 2018Chen C, Zhong Y, Wang JJ, Yu Q, Plafker K, Plafker S, Zhang SX.

(15) 3-Decylcatechol induces autophagy-mediated cell death through the IRE1α/JNK/p62 in hepatocellular carcinoma cellsOncotargetAugust 29, 2017Go DH, Lee YG, Lee DH, Kim JA, Jo IH, Han YS, Jo YH, Kim KY, Seo YK, Moon JH, et al.

(16) Luman contributes to brefeldin A-induced prion protein gene expression by interacting with the ERSE26 elementScientific reportsFebruary 13, 2017Déry MA, LeBlanc AC.

(17) Endoplasmic Reticulum Stress and Chemokine Production in Cystic Fibrosis Airway Cells: Regulation by STAT3 ModulationThe Journal of infectious diseasesJanuary 15, 2017Tang AC, Saferali A, He G, Sandford AJ, Strug LJ, Turvey SE.

(18) Endoplasmic reticulum stress enhances fibrosis through IRE1α-mediated degradation of miR-150 and XBP-1 splicingEMBO molecular medicineJuly 1, 2016Heindryckx F, Binet F, Ponticos M, Rombouts K, Lau J, Kreuger J, Gerwins P.

(19) Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathwayScientific reportsJune 3, 2016Chaveroux C, Sarcinelli C, Barbet V, Belfeki S, Barthelaix A, Ferraro-Peyret C, Lebecque S, Renno T, Bruhat A, Fafournoux P, et al.

(20) Genetic vaccines to potentiate the effective CD103+ dendritic cell-mediated cross-priming of antitumor immunityJournal of immunology (Baltimore, Md. : 1950)June 15, 2015Zhang Y, Chen G, Liu Z, Tian S, Zhang J, Carey CD, Murphy KM, Storkus WJ, Falo LD Jr, You Z.(dnXBP1) (15) were kindly provided by Dr. Glimcher (Weill Cornell Medical College). Human XBP1 shRNA (sc-38627-SH) and control shRNA DNA were purchased from Santa Cruz Biotech (Paso Robles, CA). All DNA were prepared

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