SphK2 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSphK2 shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-39225-SH
RNA TypeshRNA Clones
Vector Type (Standardized)Lentiviral
TypeshRNA Plasmid
Specieshuman
NCBI Full Gene Namesphingosine kinase 2
NCBI Gene AliasesSK 2, SK-2, SPK 2, SPK-2
Quantity20 µg

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Sphingosine is involved in PAPTP-induced death of pancreas cancer cells by interfering with mitochondrial functionsJournal of Molecular MedicineJuly 1, 2024Sameer H. Patel, Gregory C. Wilson, Yuqing Wu, Simone Keitsch, Barbara Wilker, Andrea Mattarei, Syed A. Ahmad, Ildiko Szabo, Erich Gulbinswith shRNA targeting KRAS or sphingosine kinase 2 (all from Santa Cruz Inc., #sc-35731-SH for KRAS, sc-39225-SH for sphingosine kinase 2). Cells were stably transfected by electroporation. Kv1.3 was downregulated

(2) Simultaneous targeting of mitochondrial Kv1.3 and lysosomal acid sphingomyelinase amplifies killing of pancreatic ductal adenocarcinoma cells in vitro and in vivoJournal of molecular medicine (Berlin, Germany)March 1, 2023Patel SH, Bachmann M, Kadow S, Wilson GC, Abdel-Salam MML, Xu K, Keitsch S, Soddemann M, Wilker B, Becker KA, et al.sc-41651), sphingosine kinase 1 (Santa Cruz Inc., # sc-45446) or sphingosine kinase 2 (Santa Cruz Inc., # sc-39225-SH). Control cells were transfected with an irrelevant shRNA (Santa Cruz Inc. # sc-108060). Cells were

(3) Targeting sphingosine kinase 1/2 by a novel dual inhibitor SKI-349 suppresses non-small cell lung cancer cell growthCell death & diseaseJuly 12, 2022Xue Y, Jiang K, Ou L, Shen M, Yang Y, Lu J, Xu W.

(4) TNFα mediated ceramide generation triggers cisplatin induced apoptosis in B16F10 melanoma in a PKCδ independent mannerOncotargetDecember 28, 2018Ghosh S, Jawed JJ, Halder K, Banerjee S, Chowdhury BP, Saha A, Juin SK, Majumdar SB, Bose A, Baral R, et al.

(5) Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung EndotheliumThe Journal of biological chemistryDecember 30, 2016Fu P, Ebenezer DL, Berdyshev EV, Bronova IA, Shaaya M, Harijith A, Natarajan V.

(6) Sphingosine kinase 1 is required for mesothelioma cell proliferation: role of histone acetylationPloS oneJanuary 1, 2012Kalari S, Moolky N, Pendyala S, Berdyshev EV, Rolle C, Kanteti R, Kanteti A, Ma W, He D, Husain AN, et al.

(7) Ablation of sphingosine kinase-2 inhibits tumor cell proliferation and migrationMolecular cancer research : MCRNovember 1, 2011Gao P, Smith CD.

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