ERK 2 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemERK 2 shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-35335-SH
Vector Type (Standardized)Lentiviral
NCBI Gene AliasesERK, ERK-2, ERK2, ERT1, MAPK2, NS13, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk, p42-MAPK
NCBI Full Gene Namemitogen-activated protein kinase 1
Specieshuman
TypeshRNA Plasmid
RNA TypeshRNA Clones
Quantity20 µg

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulationNature cell biologyAugust 1, 2022Guo G, Gong K, Beckley N, Zhang Y, Yang X, Chkheidze R, Hatanpaa KJ, Garzon-Muvdi T, Koduru P, Nayab A, et al.

(2) PIK3R3, part of the regulatory domain of PI3K, is upregulated in sarcoma stem-like cells and promotes invasion, migration, and chemotherapy resistanceCell death & diseaseJuly 29, 2021Yoon C, Lu J, Ryeom SW, Simon MC, Yoon SS.

(3) MicroRNA‑186‑5p downregulation inhibits osteoarthritis development by targeting MAPK1Molecular medicine reportsApril 1, 2021Li Q, Wu M, Fang G, Li K, Cui W, Li L, Li X, Wang J, Cang Y.

(4) Lymphatic metastasis-related TBL1XR1 enhances stemness and metastasis in gastric cancer stem-like cells by activating ERK1/2-SOX2 signalingOncogeneFebruary 1, 2021Lu J, Bang H, Kim SM, Cho SJ, Ashktorab H, Smoot DT, Zheng CH, Ryeom SW, Yoon SS, Yoon C, et al.

(5) BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancerCommunications biologyOctober 1, 2020Conciatori F, Bazzichetto C, Amoreo CA, Sperduti I, Donzelli S, Diodoro MG, Buglioni S, Falcone I, Shirasawa S, Blandino G, et al.

(6) ERK1/2-Nanog signaling pathway enhances CD44(+) cancer stem-like cell phenotypes and epithelial-to-mesenchymal transition in head and neck squamous cell carcinomasCell death & diseaseApril 23, 2020Huang C, Yoon C, Zhou XH, Zhou YC, Zhou WW, Liu H, Yang X, Lu J, Lee SY, Huang K.

(7) Histone deacetylase inhibition in combination with MEK or BCL-2 inhibition in multiple myelomaHaematologicaOctober 1, 2019Ramakrishnan VG, Miller KC, Macon EP, Kimlinger TK, Haug J, Kumar S, Gonsalves WI, Rajkumar SV, Kumar SK.

(8) Plumbagin Increases Paclitaxel-Induced Cell Death and Overcomes Paclitaxel Resistance in Breast Cancer Cells through ERK-Mediated Apoptosis InductionJournal of natural productsApril 26, 2019Kawiak A, Domachowska A, Lojkowska E.

(9) Interaction between p53 and Ras signaling controls cisplatin resistance via HDAC4- and HIF-1α-mediated regulation of apoptosis and autophagyTheranosticsJanuary 1, 2019Zhang X, Qi Z, Yin H, Yang G.

(10) 3-Chloroplumbagin Induces Cell Death in Breast Cancer Cells Through MAPK-Mediated Mcl-1 InhibitionFrontiers in pharmacologyJanuary 1, 2019Kawiak A, Domachowska A, Krolicka A, Smolarska M, Lojkowska E.

(11) CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK PathwayJournal of virologyDecember 15, 2018Wang L, Xie W, Zhang L, Li D, Yu H, Xiong J, Peng J, Qiu J, Sheng H, He X, et al.

(12) EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumoursOncogeneJuly 1, 2018Toosi BM, El Zawily A, Truitt L, Shannon M, Allonby O, Babu M, DeCoteau J, Mousseau D, Ali M, Freywald T, et al.5 days. To transduce cells with other shRNA constructs (Santa Cruz: shOCT4-1, sc36123-SH; shErk2-1, sc35335-SH; Sigma: shEPHB6-2 (shB6-2), TRCN0000010677; shOCT4-2 TRCN0000004882; shErk2-2, TRCN0000010040) and previously

(13) Natural Polyphenol Chlorogenic Acid Protects Against Acetaminophen-Induced Hepatotoxicity by Activating ERK/Nrf2 Antioxidative PathwayToxicological sciences : an official journal of the Society of ToxicologyMarch 1, 2018Wei M, Zheng Z, Shi L, Jin Y, Ji L.

(14) Berberine Improves Benign Prostatic Hyperplasia via Suppression of 5 Alpha Reductase and Extracellular Signal-Regulated Kinase in Vivo and in VitroFrontiers in pharmacologyJanuary 1, 2018Youn DH, Park J, Kim HL, Jung Y, Kang J, Lim S, Song G, Kwak HJ, Um JY.

(15) DDR2 facilitates papillary thyroid carcinoma epithelial mesenchymal transition by activating ERK2/Snail1 pathwayOncology lettersDecember 1, 2017Liang Z, Xie WJ, Zhao M, Cheng GP, Wu MJ.

(16) Cardiac glycosides suppress the maintenance of stemness and malignancy via inhibiting HIF-1α in human glioma stem cellsOncotargetJune 20, 2017Lee DH, Cheul Oh S, Giles AJ, Jung J, Gilbert MR, Park DM.

(17) Testosterone promotes tube formation of endothelial cells isolated from veins via activation of Smad1 proteinMolecular and cellular endocrinologyMay 5, 2017Liu P, Li X, Song F, Li P, Wei J, Yan Q, Xu X, Yang J, Li C, Fu X.

(18) The intrinsically kinase-inactive EPHB6 receptor predisposes cancer cells to DR5-induced apoptosis by promoting mitochondrial fragmentationOncotargetNovember 22, 2016El Zawily AM, Toosi BM, Freywald T, Indukuri VV, Vizeacoumar FJ, Leary SC, Freywald A.encoding DRP1 shRNA (Sigma- Aldrich, Clone ID, NM_012062.3-1244s21c1) or ERK2 shRNA (Santa Cruz, Cat # sc-35335-SH) were generated by co-transfecting HEK 293T cells at ~80% confluence in 10 cm plates with the pMD2G

(19) Immunomodulatory properties of medicinal mushrooms: differential effects of water and ethanol extracts on NK cell-mediated cytotoxicityInnate immunityOctober 1, 2016Lu CC, Hsu YJ, Chang CJ, Lin CS, Martel J, Ojcius DM, Ko YF, Lai HC, Young JD.

(20) Endoplasmic reticulum stress induces 5-fluorouracil resistance in human colon cancer cellsEnvironmental toxicology and pharmacologyJune 1, 2016Kim JK, Kang KA, Piao MJ, Ryu YS, Han X, Fernando PM, Oh MC, Park JE, Shilnikova K, Boo SJ, et al.

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