Oct-3/4 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemOct-3/4 shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-36123-SH
Quantity20 µg
RNA TypeshRNA Clones
Vector Type (Standardized)Lentiviral
TypeshRNA Plasmid
Specieshuman
NCBI Full Gene NamePOU class 5 homeobox 1
NCBI Gene AliasesOCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4, Oct3/4

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Significance of Oct-4 transcription factor as a pivotal therapeutic target for CD44(+) /24(-) mammary tumor initiating cells: Aiming at the root of the recurrenceCell biology internationalApril 1, 2023Sen U, Shanavas S, Nagendra AH, Nihad M, Chaudhury D, Rachamalla HK, Banerjee R, Shenoy P S, Bose B.

(2) Maternal diabetes-mediated RORA suppression in mice contributes to autism-like offspring through inhibition of aromataseCommunications biologyJanuary 13, 2022Yu H, Niu Y, Jia G, Liang Y, Chen B, Sun R, Wang M, Huang S, Zeng J, Lu J, et al.shRORA/shOct3/4 knockdown lentivirus The shRNA lentivirus plasmid for human RORA (sc-38868-SH), Oct3/4 (sc-36123-SH), or non-target control (sc-108060) were purchased from Santa Cruz Biotechnology. The related lentivirus

(3) Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancerMolecular cancerOctober 15, 2018Schaal CM, Bora-Singhal N, Kumar DM, Chellappan SP.

(4) Oct4 promotes cancer cell proliferation and migration and leads to poor prognosis associated with the survivin/STAT3 pathway in hepatocellular carcinomaOncology reportsAugust 1, 2018Wang G, Zhou H, Gu Z, Gao Q, Shen G.vectors. The Oct4‑shRNA and the control vector were purchased from Santa Cruz Biotechnology, Inc. (sc‑36123‑SH). HCC cells were transfected with shRNA vectors at a concentration of 4 µg/105 cells using the Lipofectamine 2000 transfection reagent

(5) EPHB6 augments both development and drug sensitivity of triple-negative breast cancer tumoursOncogeneJuly 1, 2018Toosi BM, El Zawily A, Truitt L, Shannon M, Allonby O, Babu M, DeCoteau J, Mousseau D, Ali M, Freywald T, et al.(10 µg/ml; Sigma) for 5 days. To transduce cells with other shRNA constructs (Santa Cruz: shOCT4-1, sc36123-SH; shErk2-1, sc35335-SH; Sigma: shEPHB6-2 (shB6-2), TRCN0000010677; shOCT4-2 TRCN0000004882; shErk2-2,

(6) Overexpression of OCT4 induced by modulation of histone marks plays crucial role in breast cancer progressionGeneFebruary 15, 2018Kar S, Patra SK.

(7) Differentiation-Dependent Regulation of Human Endogenous Retrovirus K Sequences and Neighboring Genes in Germ Cell Tumor CellsFrontiers in microbiologyJanuary 1, 2018Mueller T, Hantsch C, Volkmer I, Staege MS.

(8) Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expressionLeukemiaJanuary 1, 2016Huang X, Lee MR, Cooper S, Hangoc G, Hong KS, Chung HM, Broxmeyer HE.

(9) MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4OncotargetSeptember 15, 2015Lin J, Zhang L, Huang H, Huang Y, Huang L, Wang J, Huang S, He L, Zhou Y, Jia W, et al.

(10) Chronic oxidative stress leads to malignant transformation along with acquisition of stem cell characteristics, and epithelial to mesenchymal transition in human renal epithelial cellsJournal of cellular physiologyAugust 1, 2015Mahalingaiah PK, Ponnusamy L, Singh KP.

(11) OCT4 mediates FSH-induced epithelial-mesenchymal transition and invasion through the ERK1/2 signaling pathway in epithelial ovarian cancerBiochemical and biophysical research communicationsJune 5, 2015Liu L, Zhang J, Fang C, Zhang Z, Feng Y, Xi X.

(12) Multiple pluripotent stem cell markers in human anaplastic thyroid cancer: the putative upstream role of SOX2Thyroid : official journal of the American Thyroid AssociationJuly 1, 2013Carina V, Zito G, Pizzolanti G, Richiusa P, Criscimanna A, Rodolico V, Tomasello L, Pitrone M, Arancio W, Giordano C.

(13) Drug-induced senescence generates chemoresistant stemlike cells with low reactive oxygen speciesThe Journal of biological chemistryOctober 28, 2011Achuthan S, Santhoshkumar TR, Prabhakar J, Nair SA, Pillai MR.

(14) Epithelial to mesenchymal transition is mechanistically linked with stem cell signatures in prostate cancer cellsPloS oneAugust 27, 2010Kong D, Banerjee S, Ahmad A, Li Y, Wang Z, Sethi S, Sarkar FH.

(15) Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential Oct4-AKT-ATP-binding cassette G2 pathwayHepatology (Baltimore, Md.)August 1, 2010Wang XQ, Ongkeko WM, Chen L, Yang ZF, Lu P, Chen KK, Lopez JP, Poon RT, Fan ST.

(16) Loss of Oct-3/4 expression in embryonal carcinoma cells is associated with induction of cisplatin resistanceTumour biology : the journal of the International Society for Oncodevelopmental Biology and MedicineJanuary 1, 2006Mueller T, Mueller LP, Luetzkendorf J, Voigt W, Simon H, Schmoll HJ.

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