HSP 27 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemHSP 27 shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-29350-SH
Quantity20 µg
RNA TypeshRNA Clones
TypeshRNA Plasmid
Specieshuman
NCBI Full Gene Nameheat shock protein family B (small) member 1
NCBI Gene AliasesCMT2F, HEL-S-102, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27
Vector Type (Standardized)Lentiviral

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agentsBioorganic chemistryJanuary 1, 2023Choi SK, Hwang SY, Jeon S, Yoo H, Lee J, Shin JH, Na Y, Kwon Y, Lee YS.

(2) Hyperthermia increases HSP production in human PDMCs by stimulating ROS formation, p38 MAPK and Akt signaling, and increasing HSF1 activityStem cell research & therapyJune 3, 2022Liu JF, Chen PC, Ling TY, Hou CH.

(3) Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 DimersPharmaceuticsApril 28, 2021Yoo H, Choi SK, Lee J, Park SH, Park YN, Hwang SY, Shin JH, Na Y, Kwon Y, Lee HJ, et al.

(4) Heat Shock Protein 27 Regulates the Inflammatory Response of Intestinal Epithelial Cells by the Nuclear Factor-κB PathwayDigestive diseases and sciencesDecember 1, 2020Zhang Y, Wang X, Wang S, Yan Z, Li C, Zheng Y, Cui L.

(5) Treatment of human neuroblastoma cell line SH-SY5Y with HSP27 siRNA tagged-exosomes decreased differentiation rate into mature neuronsJournal of cellular physiologyNovember 1, 2019Shokrollahi E, Nourazarian A, Rahbarghazi R, Salimi L, Karbasforush S, Khaksar M, Salarinasab S, Abhari A, Heidarzadeh M.

(6) The Hsp27-Mediated IkBα-NFκB Signaling Axis Promotes Radiation-Induced Lung FibrosisClinical cancer research : an official journal of the American Association for Cancer ResearchSeptember 1, 2019Kim JY, Jeon S, Yoo YJ, Jin H, Won HY, Yoon K, Hwang ES, Lee YJ, Na Y, Cho J, et al.

(7) Up-regulation of heat shock protein 27 inhibits apoptosis in lumbosacral nerve root avulsion-induced neuronsScientific reportsAugust 7, 2019Zhou ZB, Huang GX, Lu JJ, Ma J, Yuan QJ, Cao Y, Zhu L.105 cells/plate and cultured overnight. The SH-SY5Y cells were transfected with Hsp27 shRNA plasmid (sc-29350-SH, Santa Cruz Biotechnology) or control shRNA plasmid (sc-108060, Santa Cruz Biotechnology) using Lipofectamine 2000 Transfection Reagent

(8) Decreasing O-GlcNAcylation affects the malignant transformation of MCF-7 cells via Hsp27 expression and its O-GlcNAc modificationOncology reportsOctober 1, 2018Netsirisawan P, Chaiyawat P, Chokchaichamnankit D, Lirdprapamongkol K, Srisomsap C, Svasti J, Champattanachai V.

(9) Cell Cycle Arrest and Apoptosis Induced by Porphyromonas gingivalis Require Jun N-Terminal Protein Kinase- and p53-Mediated p38 Activation in Human TrophoblastsInfection and immunityApril 1, 2018Inaba H, Amano A, Lamont RJ, Murakami Y, Matsumoto-Nakano M.

(10) Synthesis and biological effect of chrom-4-one derivatives as functional inhibitors of heat shock protein 27European journal of medicinal chemistryOctober 20, 2017Hwang SY, Kwak SY, Kwon Y, Lee YS, Na Y.

(11) Acetylation-induced TDP-43 pathology is suppressed by an HSF1-dependent chaperone programNature communicationsJuly 19, 2017Wang P, Wander CM, Yuan CX, Bereman MS, Cohen TJ.

(12) Overcoming HSP27-mediated resistance by altered dimerization of HSP27 using small moleculesOncotargetAugust 16, 2016Kim JH, Jung YJ, Choi B, Lee NL, Lee HJ, Kwak SY, Kwon Y, Na Y, Lee YS.NCI-H460 cell lines expressing shRNA for HSP27 (puromycin resistance gene). The HSP27 shRNA plasmid (sc-29350-SH), and shRNA plasmid transfection reagent (sc-108061) were ordered from Santa Cruz Biotechnology. To

(13) Up-regulation of Hsp27 by ERα/Sp1 facilitates proliferation and confers resistance to apoptosis in human papillary thyroid cancer cellsMolecular and cellular endocrinologyAugust 15, 2016Mo XM, Li L, Zhu P, Dai YJ, Zhao TT, Liao LY, Chen GG, Liu ZM.

(14) Quercetin blocks t-AUCB-induced autophagy by Hsp27 and Atg7 inhibition in glioblastoma cells in vitroJournal of neuro-oncologyAugust 1, 2016Li J, Tang C, Li L, Li R, Fan Y.

(15) Quercetin sensitizes glioblastoma to t-AUCB by dual inhibition of Hsp27 and COX-2 in vitro and in vivoJournal of experimental & clinical cancer research : CRApril 2, 2016Li J, Tang C, Li L, Li R, Fan Y.

(16) The molecular and clinical verification of therapeutic resistance via the p38 MAPK-Hsp27 axis in lung cancerOncotargetMarch 22, 2016Liu CL, Chen SF, Wu MZ, Jao SW, Lin YS, Yang CY, Lee TY, Wen LW, Lan GL, Nieh S.

(17) HSPB1 Inhibits the Endothelial-to-Mesenchymal Transition to Suppress Pulmonary Fibrosis and Lung TumorigenesisCancer researchMarch 1, 2016Choi SH, Nam JK, Kim BY, Jang J, Jin YB, Lee HJ, Park S, Ji YH, Cho J, Lee YJ.

(18) Phosphorylation of AKT induced by phosphorylated Hsp27 confers the apoptosis-resistance in t-AUCB-treated glioblastoma cells in vitroJournal of neuro-oncologyJanuary 1, 2015Li R, Li J, Sang D, Lan Q.

(19) Interferon-β counter-regulates its own pro-apoptotic action by activating p38 MAPK signalling in human SH-SY5Y neuroblastoma cellsApoptosis : an international journal on programmed cell deathOctober 1, 2014Dedoni S, Olianas MC, Onali P.

(20) Epidermal growth factor/heat shock protein 27 pathway regulates vasculogenic mimicry activity of breast cancer stem/progenitor cellsBiochimieSeptember 1, 2014Lee CH, Wu YT, Hsieh HC, Yu Y, Yu AL, Chang WW.

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