Notch 3 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemNotch 3 shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-37135-SH
RNA TypeshRNA Clones
Vector Type (Standardized)Lentiviral
Quantity20 µg
NCBI Gene AliasesCADASIL, CADASIL1, CASIL, IMF2, LMNS
NCBI Full Gene Namenotch receptor 3
Specieshuman
TypeshRNA Plasmid

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Endothelial cell senescence exacerbates pulmonary hypertension by inducing juxtacrine Notch signaling in smooth muscle cellsiScienceMay 19, 2023Ramadhiani R, Ikeda K, Miyagawa K, Ryanto GRT, Tamada N, Suzuki Y, Kirita Y, Matoba S, Hirata KI, Emoto N.(#VSC11649, Dharmacon), while lentiviruses delivering Notch3 shRNA was produced using Notch3 shRNA plasmid (#sc-37135-SH, Santa Cruz). These shRNA plasmids were transfected into 293T cells alongside with pMD2.G and psPAX2

(2) NOTCH3, a crucial target of miR-491-5p/miR-875-5p, promotes gastric carcinogenesis by upregulating PHLDB2 expression and activating Akt pathwayOncogeneMarch 1, 2021Kang W, Zhang J, Huang T, Zhou Y, Wong CC, Chan RCK, Dong Y, Wu F, Zhang B, Wu WKK, et al.depletion, the NOTCH3 was downregulated by shRNA-mediated knockdown in MGC-803 cells (shNOTCH3 plasmid, sc-37135-SH, Santa Cruz). Then the shNOTCH3 transfected cells and their counterparts were subcutaneously injected

(3) Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein responseOncogenesisOctober 18, 2020Giuli MV, Diluvio G, Giuliani E, Franciosa G, Di Magno L, Pignataro MG, Tottone L, Nicoletti C, Besharat ZM, Peruzzi G, et al.

(4) Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagationOncogeneDecember 1, 2018Ferrandino F, Bernardini G, Tsaouli G, Grazioli P, Campese AF, Noce C, Ciuffetta A, Vacca A, Besharat ZM, Bellavia D, et al.

(5) NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrestOncogenesisMay 25, 2018Diluvio G, Del Gaudio F, Giuli MV, Franciosa G, Giuliani E, Palermo R, Besharat ZM, Pignataro MG, Vacca A, d'Amati G, et al.

(6) Notch3 expression correlates with thyroid cancer differentiation, induces apoptosis, and predicts disease prognosisCancerMarch 1, 2017Somnay YR, Yu XM, Lloyd RV, Leverson G, Aburjania Z, Jang S, Jaskula-Sztul R, Chen H.

(7) Association between high levels of Notch3 expression and high invasion and poor overall survival rates in pancreatic ductal adenocarcinomaOncology reportsNovember 1, 2016Zhou JX, Zhou L, Li QJ, Feng W, Wang PM, Li EF, Gong WJ, Kou MW, Gou WT, Yang YL.

(8) Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progressionOncogeneSeptember 8, 2016Franciosa G, Diluvio G, Gaudio FD, Giuli MV, Palermo R, Grazioli P, Campese AF, Talora C, Bellavia D, D'Amati G, et al.

(9) Tumor-suppressor role of Notch3 in medullary thyroid carcinoma revealed by genetic and pharmacological inductionMolecular cancer therapeuticsFebruary 1, 2015Jaskula-Sztul R, Eide J, Tesfazghi S, Dammalapati A, Harrison AD, Yu XM, Scheinebeck C, Winston-McPherson G, Kupcho KR, Robers MB, et al.

(10) Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemiaLeukemiaDecember 1, 2014Kumar V, Palermo R, Talora C, Campese AF, Checquolo S, Bellavia D, Tottone L, Testa G, Miele E, Indraccolo S, et al.

(11) Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinomaOncotargetJune 15, 2014Capaccione KM, Hong X, Morgan KM, Liu W, Bishop JM, Liu L, Markert E, Deen M, Minerowicz C, Bertino JR, et al.

(12) Notch3 is activated by chronic hypoxia and contributes to the progression of human prostate cancerInternational journal of cancerDecember 1, 2013Danza G, Di Serio C, Ambrosio MR, Sturli N, Lonetto G, Rosati F, Rocca BJ, Ventimiglia G, del Vecchio MT, Prudovsky I, et al.

(13) The significance of Notch1 compared with Notch3 in high metastasis and poor overall survival in hepatocellular carcinomaPloS oneJanuary 1, 2013Zhou L, Zhang N, Song W, You N, Li Q, Sun W, Zhang Y, Wang D, Dou K.

(14) Cyclin D1 is a direct target of JAG1-mediated Notch signaling in breast cancerBreast cancer research and treatmentAugust 1, 2010Cohen B, Shimizu M, Izrailit J, Ng NF, Buchman Y, Pan JG, Dering J, Reedijk M.

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