TFEB shRNA Plasmid (m) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemTFEB shRNA Plasmid (m)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-38510-SH
Quantity20 µg
RNA TypeshRNA Clones
Vector Type (Standardized)Lentiviral
TypeshRNA Plasmid
Speciesmouse
NCBI Full Gene Nametranscription factor EB
NCBI Gene AliasesTcfeb, bHLHe35

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Metformin-induced TTP mediates communication between Kupffer cells and hepatocytes to alleviate hepatic steatosis by regulating lipophagy and necroptosisMetabolism: clinical and experimentalApril 1, 2023Park J, Rah SY, An HS, Lee JY, Roh GS, Ryter SW, Park JW, Yang CH, Surh YJ, Kim UH, et al.

(2) MEK1/2 inhibition rescues neurodegeneration by TFEB-mediated activation of autophagic lysosomal function in a model of Alzheimer's DiseaseMolecular psychiatryNovember 1, 2022Chun YS, Kim MY, Lee SY, Kim MJ, Hong TJ, Jeon JK, Ganbat D, Kim HT, Kim SS, Kam TI, et al.penicillin and 100 μg/ml streptomycin. The shRNAs [control (Santa Cruz, sc-108060), TFEB (Santa Cruz, sc-38510-SH), MEK1 (Dharmacon, V3SM11241-234594572), and MEK2 (Dharmacon, V3SM11241-235104473)] were transfected

(3) 7-ketocholesterol enhances autophagy via the ROS-TFEB signaling pathway in osteoclastsThe Journal of nutritional biochemistryOctober 1, 2021Sul OJ, Li G, Kim JE, Kim ES, Choi HS.

(4) The Peroxisome Proliferator-Activated Receptor α- Agonist Gemfibrozil Promotes Defense Against Mycobacterium abscessus InfectionsCellsMarch 6, 2020Kim YS, Kim JK, Hanh BTB, Kim SY, Kim HJ, Kim YJ, Jeon SM, Park CR, Oh GT, Park JW, et al.Watertown, MA, USA, deposited by Dr. Didier Trono) and mouse Tfeb shRNA (Santa Cruz Biotechnology, sc-38510-SH) were cotransfected into HEK293T cells using Lipofectamine 2000 (Invitrogen, 11668-019). After 72 h,

(5) Simvastatin improves lysosome function via enhancing lysosome biogenesis in endothelial cellsFrontiers in bioscience (Landmark edition)January 1, 2020Zhang Y, Wang YT, Koka S, Zhang Y, Hussain T, Li X.

(6) Contribution of transcription factor EB to adipoRon-induced inhibition of arterial smooth muscle cell proliferation and migrationAmerican journal of physiology. Cell physiologyNovember 1, 2019Wang YT, Chen J, Li X, Umetani M, Chen Y, Li PL, Zhang Y.

(7) Activation of TFEB ameliorates dedifferentiation of arterial smooth muscle cells and neointima formation in mice with high-fat dietCell death & diseaseSeptember 12, 2019Wang YT, Li X, Chen J, McConnell BK, Chen L, Li PL, Chen Y, Zhang Y.

(8) Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injuryCell death & diseaseOctober 17, 2018Kim HJ, Joe Y, Rah SY, Kim SK, Park SU, Park J, Kim J, Ryu J, Cho GJ, Surh YJ, et al.

(9) A randomized clinical trial evaluating choroidal blood flow and morphology after conventional and pattern scan laser panretinal photocoagulationScientific reportsSeptember 20, 2018Mikoshiba Y, Iwase T, Ueno Y, Yamamoto K, Ra E, Terasaki H.

(10) Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EBJournal of immunology (Baltimore, Md. : 1950)June 1, 2018Hayama Y, Kimura T, Takeda Y, Nada S, Koyama S, Takamatsu H, Kang S, Ito D, Maeda Y, Nishide M, et al.

(11) TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehaloseAutophagyJanuary 1, 2018Zhang Y, Higgins CB, Mayer AL, Mysorekar IU, Razani B, Graham MJ, Hruz PW, DeBosch BJ.

(12) Identification of ANXA2 (annexin A2) as a specific bleomycin target to induce pulmonary fibrosis by impeding TFEB-mediated autophagic fluxAutophagyJanuary 1, 2018Wang K, Zhang T, Lei Y, Li X, Jiang J, Lan J, Liu Y, Chen H, Gao W, Xie N, et al.

(13) PPAR-α Activation Mediates Innate Host Defense through Induction of TFEB and Lipid CatabolismJournal of immunology (Baltimore, Md. : 1950)April 15, 2017Kim YS, Lee HM, Kim JK, Yang CS, Kim TS, Jung M, Jin HS, Kim S, Jang J, Oh GT, et al.previously (22). For silencing target genes in BMDM, the pLKO.1-based lentiviral shRNA construct, TFEB (sc-38510SH; Santa Cruz), was used. Briefly, the lentivirus was generated by transfection of HEK293T cells with

(14) Melatonin antagonizes cadmium-induced neurotoxicity by activating the transcription factor EB-dependent autophagy-lysosome machinery in mouse neuroblastoma cellsJournal of pineal researchOctober 1, 2016Li M, Pi H, Yang Z, Reiter RJ, Xu S, Chen X, Chen C, Zhang L, Yang M, Li Y, et al.

(15) Deacetylation of TFEB promotes fibrillar Aβ degradation by upregulating lysosomal biogenesis in microgliaProtein & cellJune 1, 2016Bao J, Zheng L, Zhang Q, Li X, Zhang X, Li Z, Bai X, Zhang Z, Huo W, Zhao X, et al.

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