Chk2 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemChk2 shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-29271-SH
RNA TypeshRNA Clones
Vector Type (Standardized)Lentiviral
TypeshRNA Plasmid
Specieshuman
NCBI Full Gene Namecheckpoint kinase 2
NCBI Gene AliasesCDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1
Quantity20 µg

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Checkpoint Kinase 2 Inhibition Can Reverse Tamoxifen Resistance in ER-Positive Breast CancerInternational journal of molecular sciencesOctober 14, 2022Tsoi H, Tsang WC, Man EPS, Leung MH, You CP, Chan SY, Chan WL, Khoo US.mycoplasma. 4.2. Plasmids, siRNA, shRNA and RT-qPCR pcDNA3.1-His-BQ323636.1 was used. CHK2 human shRNA plasmid (sc-29271-SH; Santa Cruz Biotechnology, Dallas, TX, USA) was employed, and control shRNA (sc-108080; Santa Cruz Biotechnology,

(2) Study on the Mechanism of Cell Cycle Checkpoint Kinase 2 (CHEK2) Gene Dysfunction in Chemotherapeutic Drug Resistance of Triple Negative Breast Cancer CellsMedical science monitor : international medical journal of experimental and clinical researchMay 15, 2018Luo L, Gao W, Wang J, Wang D, Peng X, Jia Z, Jiang Y, Li G, Tang D, Wang Y.

(3) Camptothecin induces G(2)/M phase arrest through the ATM-Chk2-Cdc25C axis as a result of autophagy-induced cytoprotection: Implications of reactive oxygen speciesOncotargetApril 24, 2018Prasad Tharanga Jayasooriya RG, Dilshara MG, Neelaka Molagoda IM, Park C, Park SR, Lee S, Choi YH, Kim GY.

(4) Ape1 guides DNA repair pathway choice that is associated with drug tolerance in glioblastomaScientific reportsAugust 29, 2017Ströbel T, Madlener S, Tuna S, Vose S, Lagerweij T, Wurdinger T, Vierlinger K, Wöhrer A, Price BD, Demple B, et al.

(5) Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell lineOncology reportsNovember 1, 2014Ling H, Lu LF, He J, Xiao GH, Jiang H, Su Q.

(6) HuR regulates alternative splicing of the TRA2β gene in human colon cancer cells under oxidative stressMolecular and cellular biologyAugust 1, 2014Akaike Y, Masuda K, Kuwano Y, Nishida K, Kajita K, Kurokawa K, Satake Y, Shoda K, Imoto I, Rokutan K.

(7) Chk2 prevents mitotic exit when the majority of kinetochores are unattachedThe Journal of cell biologyMay 12, 2014Petsalaki E, Zachos G.

(8) Kaposi sarcoma herpes virus latency associated nuclear antigen protein release the G2/M cell cycle blocks by modulating ATM/ATR mediated checkpoint pathwayPloS oneJanuary 1, 2014Kumar A, Sahu SK, Mohanty S, Chakrabarti S, Maji S, Reddy RR, Jha AK, Goswami C, Kundu CN, Rajasubramaniam S, et al.

(9) Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAsNucleic acids researchJanuary 1, 2014Yoon JH, Abdelmohsen K, Srikantan S, Guo R, Yang X, Martindale JL, Gorospe M.

(10) FOXO3 signalling links ATM to the p53 apoptotic pathway following DNA damageNature communicationsJanuary 1, 2012Chung YM, Park SH, Tsai WB, Wang SY, Ikeda MA, Berek JS, Chen DJ, Hu MC.

(11) Functional and molecular interactions between ERK and CHK2 in diffuse large B-cell lymphomaNature communicationsJuly 19, 2011Dai B, Zhao XF, Mazan-Mamczarz K, Hagner P, Corl S, Bahassi el M, Lu S, Stambrook PJ, Shapiro P, Gartenhaus RB.

(12) Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiationThe EMBO journalMarch 16, 2011Masuda K, Abdelmohsen K, Kim MM, Srikantan S, Lee EK, Tominaga K, Selimyan R, Martindale JL, Yang X, Lehrmann E, et al.

(13) Gain of cellular adaptation due to prolonged p53 impairment leads to functional switchover from p53 to p73 during DNA damage in acute myeloid leukemia cellsThe Journal of biological chemistryOctober 22, 2010Chakraborty J, Banerjee S, Ray P, Hossain DMS, Bhattacharyya S, Adhikary A, Chattopadhyay S, Das T, Sa G.

(14) Chk1 inhibition after replicative stress activates a double strand break response mediated by ATM and DNA-dependent protein kinaseCell cycle (Georgetown, Tex.)March 1, 2010McNeely S, Conti C, Sheikh T, Patel H, Zabludoff S, Pommier Y, Schwartz G, Tse A.

(15) Induction of a reversible, non-cytotoxic S-phase delay by resveratrol: implications for a mechanism of lifespan prolongation and cancer protectionBritish journal of pharmacologySeptember 1, 2009Zhou R, Fukui M, Choi HJ, Zhu BT.

(16) Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phaseCarcinogenesisJune 1, 2008Stolfi C, Fina D, Caruso R, Caprioli F, Fantini MC, Rizzo A, Sarra M, Pallone F, Monteleone G.

(17) Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarinOncogeneFebruary 16, 2006Deep G, Singh RP, Agarwal C, Kroll DJ, Agarwal R.

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