Skp2 p45 shRNA Plasmid (h) from Santa Cruz Biotechnology, Inc.

Product Specs
ItemSkp2 p45 shRNA Plasmid (h)
CompanySanta Cruz Biotechnology, Inc.
Price $592.00Supplier Page View Company Product Page
Catalog Numbersc-36499-SH
Quantity20 µg
TypeshRNA Plasmid
Specieshuman
NCBI Full Gene NameS-phase kinase associated protein 2
NCBI Gene AliasesFBL1, FBXL1, FLB1, p45
RNA TypeshRNA Clones
Vector Type (Standardized)Lentiviral

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Santa Cruz Biotechnology, Inc.

10410 Finnell Street

Dallas, Texas 75220

United States

Phone: 1-800-457-3801
831-457-3801

Company Profile

Website: http://www.scbt.com/

(1) Aurora-A/FOXO3A/SKP2 axis promotes tumor progression in clear cell renal cell carcinoma and dual-targeting Aurora-A/SKP2 shows synthetic lethalityCell death & diseaseJuly 13, 2022Li P, Chen T, Kuang P, Liu F, Li Z, Liu F, Wang Y, Zhang W, Cai X.

(2) CDK2-instigates C/EBPα degradation through SKP2 in Acute myeloid leukemiaMedical oncology (Northwood, London, England)May 17, 2021Thacker G, Mishra M, Sharma A, Singh AK, Sanyal S, Trivedi AK.

(3) E3 ligase SCF(SKP2) ubiquitinates and degrades tumor suppressor C/EBPα in acute myeloid leukemiaLife sciencesSeptember 15, 2020Thacker G, Mishra M, Sharma A, Singh AK, Sanyal S, Trivedi AK.

(4) miR-1297 Promotes Cell Proliferation of Non-Small Cell Lung Cancer Cells: Involving in PTEN/Akt/Skp2 Signaling PathwayDNA and cell biologyNovember 1, 2017Bu W, Luo T.

(5) A novel read-through transcript JMJD7-PLA2G4B regulates head and neck squamous cell carcinoma cell proliferation and survivalOncotargetJanuary 10, 2017Cheng Y, Wang Y, Li J, Chang I, Wang CY.

(6) Skp2 inhibits osteogenesis by promoting ubiquitin-proteasome degradation of Runx2Biochimica et biophysica actaApril 1, 2016Thacker G, Kumar Y, Khan MP, Shukla N, Kapoor I, Kanaujiya JK, Lochab S, Ahmed S, Sanyal S, Chattopadhyay N, et al.

(7) Inhibition of S-phase kinase-associated protein 2-mediated p27 degradation suppresses tumorigenesis and the progression of hepatocellular carcinomaMolecular medicine reportsMay 1, 2015Qi M, Liu D, Zhang S, Hu P, Sang T.

(8) The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growthOncotargetAugust 15, 2014Tsai YS, Lai CL, Lai CH, Chang KH, Wu K, Tseng SF, Fazli L, Gleave M, Xiao G, Gandee L, et al.K334R, and K246R/K248R/K334R) using site-directed mutagenesis kits (QuikChange®, Stratagene). Skp2shRNA (sc-36499-SH) and its control plasmid were purchased from Santa Cruz Biotechnology. Skp2 cDNA and its derivative

(9) Co-treatment with quercetin and 1,2,3,4,6-penta-O-galloyl-β-D-glucose causes cell cycle arrest and apoptosis in human breast cancer MDA-MB-231 and AU565 cellsJournal of agricultural and food chemistryJuly 3, 2013Huang C, Lee SY, Lin CL, Tu TH, Chen LH, Chen YJ, Huang HC.

(10) Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancerPloS oneJanuary 1, 2012Huang KT, Pavlides SC, Lecanda J, Blank SV, Mittal KR, Gold LI.

(11) 1,2,3,4,6-penta-O-galloyl-β-D-glucose, quercetin, curcumin and lycopene induce cell-cycle arrest in MDA-MB-231 and BT474 cells through downregulation of Skp2 proteinJournal of agricultural and food chemistryJune 22, 2011Huang HC, Lin CL, Lin JK.

(12) Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2Neoplasia (New York, N.Y.)June 1, 2011Pernicová Z, Slabáková E, Kharaishvili G, Bouchal J, Král M, Kunická Z, Machala M, Kozubík A, Souček K.

(13) p27-Associated G1 arrest induced by hinokitiol in human malignant melanoma cells is mediated via down-regulation of pRb, Skp2 ubiquitin ligase, and impairment of Cdk2 functionCancer lettersDecember 28, 2009Liu S, Yamauchi H.

(14) SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosisGastroenterologyNovember 1, 2009Calvisi DF, Ladu S, Pinna F, Frau M, Tomasi ML, Sini M, Simile MM, Bonelli P, Muroni MR, Seddaiu MA, et al.

(15) Phosphorylation of p27Kip1 by Epstein-Barr virus protein kinase induces its degradation through SCFSkp2 ubiquitin ligase actions during viral lytic replicationThe Journal of biological chemistryJuly 10, 2009Iwahori S, Murata T, Kudoh A, Sato Y, Nakayama S, Isomura H, Kanda T, Tsurumi T.

(16) EGCG stabilizes p27kip1 in E2-stimulated MCF-7 cells through down-regulation of the Skp2 proteinEndocrinologyDecember 1, 2008Huang HC, Way TD, Lin CL, Lin JK.

(17) Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7Molecular biology of the cellNovember 1, 2008Xu G, Bernaudo S, Fu G, Lee DY, Yang BB, Peng C.

(18) p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cellsMolecular cancer therapeuticsOctober 1, 2007Roy S, Kaur M, Agarwal C, Tecklenburg M, Sclafani RA, Agarwal R.

(19) Up-regulation of Skp2 after prostate cancer cell adhesion to basement membranes results in BRCA2 degradation and cell proliferationThe Journal of biological chemistryAugust 4, 2006Moro L, Arbini AA, Marra E, Greco M.

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