DS-11 Series Spectrophotometer / Fluorometer from DeNovix Inc.

Product Specs
ItemDS-11 Series Spectrophotometer / Fluorometer
CompanyDeNovix Inc.
Price Get Pricing
Catalog NumberDS-11 / DS-11+ / DS-11 FX / DS-11 FX+
Accuracy1.5% Absorbance Accuracy at 0.75 AU at 260 nm
Wavelength(s)UV-Vis: 190 to 840 nm, Green LED: 525 nm (490-558 nm Excitation), 565-650 nm (Emission), Red LED: 635 nm (613-662 nm Excitation), 665-740 nm (Emission), Blue LED: 470 nm (442-497 nm Excitation), 514-567 nm (Emission), UV: 375 nm (361-389 nm Excitation), 435-485 nm (Emission)
Resolution1.5 nm (FWHM at Hg 253.7 nm)
Light SourcePulsed Xenon flash lamp
Sample Volume0.5 to 1 µl
TypeUV-Vis Spectrophotometer, Fluorometer, Small Volume
QuantityEA
Applications1 µL UV-Vis or cuvette Absorbance DNA, RNA, ssDNA quantification with purity measurements (260/280 and 260/230 ratios), Purified protein (A280) up to 750mg/ml BSA, Peptide analysis (A205/215), Fluorescent quantification assays (preconfigured or custom)
Detection2048 Element CCD, Photodiode
Wavelength Accuracy0.5 nm (UV-Vis)
Dimensions(WxL) 20 x 33 cm
Measurement Time2 seconds
ConnectivityWi-Fi, Ethernet, 3 USB ports
Optical SystemSingle-Beam
Sample Type0.5 µL min volume
Display7" HD Touchscreen

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DeNovix Inc.

3411 Silverside Rd

Hanby Building

Wilmington, DE 19810

United States

Phone: +1 302 442 6911
fax +1 302 792 7400

Company Profile

Website: www.denovix.com

(1) Ovalbumin, lysozyme, and ovomucoid gene polymorphisms: Implications for hatchability in Japanese quailPoultry ScienceMay 1, 2026S. Knaga, K. Kasperek, G. Ziębamanufacturer’s instructions. DNA concentration and purity were assessed spectrophotometrically using a Denovix DS-11+ UV-Vis spectrophotometer (DeNovix, Wilmington, DE, USA), and quality was evaluated by electrophoresis

(2) Reprogramming of bacterial virulence by lysine acetylationNat CommunApril 27, 2026Ole Schmöker, Britta Girbardt, Sabrina Schulze, Gottfried J. Palm, Leona Berndt, Jens Hoppen, Nilüfer Kara, Xenia Schöps, Ruba Al-Abdulla, Klara Garz, et al.before protein concentration was determined by measuring absorption at 280 nm using a spectrophotometer DS-11 FX (DeNovix, Wilmington USA). ExPASy ProtParam was used to obtain extinction coefficients and molecular

(3) Enhanced Bioactivity of Puerariae Radix- Hovenia Seed Extracts Through Lactiplantibacillus plantarum and Lacticaseibacillus paracasei Co-Fermentation: Impact on Alcoholic Liver Injury and Macrophage PolarizationFood Sci NutrApril 25, 2026Yunpeng Sun, Shen Yao, Yuan Cui, Yiyu Ni, Meichen Liu, Daqing Zhao, Shiting Yu, Siming Wangextracted using the RNAsimple Total RNA Kit (Tiangen, China). RNA concentration was measured using a DS‐11 FX+ spectrophotometer (DeNovix, USA). The extracted RNA was then reverse‐transcribed into cDNA using the

(4) Helminthological Survey of the European Brown Hare (Lepus europaeus) in Türkiye, with A Note on Haplotype and Network Analyses of Dicrocoelium dendriticum and Passalurus ambiguusActa ParasitolApril 21, 2026Kadir Kalkan, Ufuk Erol, Omer Faruk Sahin, Husnu Furkan Sakar, Kursat Altayinstructions. After the DNA extraction process, the obtained DNA was measured with a NanoDrop (Denovix Ds-11, USA), and samples were stored at − 20 °C until the PCR assay. The PCR assay was carried out using primers

(5) Population differences of chromosome 22q11.2 duplication structure predispose differentially to microdeletion and inversionNat CommunApril 18, 2026David Porubsky, DongAhn Yoo, Nidhi Koundinya, Erika Souche, Philip C. Dishuck, Nicolas Dierckxsens, William T. Harvey, Katherine M. Munson, Kendra Hoekzema, Daniel D. Chan, et al.At all steps, quantification was performed with Qubit dsDNA HS (Thermo Fisher, Q32854), measured on DS-11 FX (Denovix), and size distribution checked using FEMTO Pulse (Agilent, M5330AA & FP-1002-0275.) HMW DNA

(6) Oxidative Stress, DNA Damage, DNA Repair Inhibition, and Apoptosis Induced by Lead and Cadmium Combined Exposure in TK6 CellsToxicsApril 18, 2026Xin Liu, Zhiyuan Han, Kuibin Han, Yuhan Pang, Xiaoyue Zhao, Yuting Wang, Xiaoyan Wu, Tuanwei Wangvalue at 230, 260, and 280 nm using an ultramicro spectrophotometer (Denovix, Wilmington, DE, USA; DS-11+), and required an A260/A280 ratio between 1.8 and 2.0, and an A260/A230 ratio greater than 2. First-strand

(7) Biophysical characterization of Cyclophilin B reveals membrane localization as its primary functional determinant as a prolyl isomeraseProtein SciApril 16, 2026Sarah C. DeVoe, Thomas C. Yost, Ashley J. Newton, Gavin A. Grever, Melissa Fernandez Ayala, Wendell P. Griffith, Robert D. Latvala, Philipp A. M. SchmidpeterMWCO) to about 2 mL, and the final protein concentration was determined using a microspectrophotometer (DS‐11+, DeNovix) and extinction coefficients of 8730 M−1 cm−1 for CypA and 16,960 M−1 cm−1 for CypB. CypD

(8) Regorafenib-Induced Stress Response Alters the Bioenergetic Profile of Osteosarcoma Cells and Modulates Gene Expression Associated with Metabolic regulation-a Potential Mechanism of Osteosarcoma Treatment-Related AdaptationCancer Manag ResApril 16, 2026Klaudia Marcinkowska, Anna Raciborska, Bożena Obmińska-Mrukowicz, Agnieszka ŚmieszekPoland), and its concentration and purity were assessed spectrophotometrically at 260 and 280 nm using a DS-11 Fx spectrophotometer (Denovix, Wilmington, DE, USA). To ensure RNA integrity, DNase I digestion using PrecisionDNAse

(9) Cocaine remodels m6A RNA-dependent signaling to drive locomotor plasticity in Drosophila melanogasterFront Cell NeurosciApril 15, 2026Ana Filošević Vujnović, Nina Milotić, Bobana Samardžija, Marko Rubinić, Rozi Andretić Waldowski, Alessia Soldanoto 60 °C. RNA concentration and purity were determined using a NanoDrop spectrophotometer (DeNovix DS-11) at 260 nm. The 260/280 and 260/230 absorbance ratios were used to assess RNA quality, while RNA samples

(10) Bovine endometrial organoids: a new tool to study conceptus-maternal interactions in mammals†Biology of ReproductionApril 13, 2026Jessica C Edge, Olga Amelkina, Haidee Tinning, Gianluca Giovanardi, Elena Mancinelli, Samantha Gardner, Elton J R Vasconcelos, Virginia Pensabene, Karen Forbes, Mary J O'Connell, et al.digestion as per manufacturer’s protocol (Qiagen). RNA concentration was determined using the DeNovix DS-11 FX+ spectrophotometer (DeNovix). Extracted RNA was reverse transcribed using the High-Capacity cDNA reverse

(11) Circadian Controlled Transcription in Brain and Peripheral Organs of Juvenile and Adult MiceInt J Mol SciApril 10, 2026Yasemin Kubra Akyel, Kaan Arslan, Cansu Kose, Aziz Sancarinstructions, including on-column DNase I treatment. RNA concentration and purity were assessed by DS-11 microvolume UV–Vis spectrophotometer (DeNovix, Wilmington, DE, USA), and samples were submitted to Novogene

(12) Spatial and temporal variation in bacterial-archaeal community and niche differentiation of denitrifying anaerobic methane-oxidizing microbes in grass carp (Ctenopharyngodon idellus) aquaculture ponds of Northern ChinaFront MicrobiolApril 10, 2026Yan Chen, Zhe Pan, Zhaoxing Wu, Zhaohui TianDNA purity and concentration were checked by 1.2% agarose gel electrophoresis and spectrophotometry (DS-11 UV–Vis spectrophotometer, DeNovix, United States). The primer pairs 515F (GTGYCAGCMGCCGCGGTAA)/806R

(13) Inward Rectifier Potassium (Kir) Channel Inhibitors Protect Citrus from the Asian Citrus Psyllid by Inducing Toxicity and Inhibition of FeedingJournal of Agricultural and Food ChemistryApril 8, 2026Flinn O’Hara, Alexandra Cremades, Na Xie, Erik L. Roldán, Miltan Chandra Roy, Sandipa Gautam, Mamoudou Setamou, Amar Chittiboyina, Troy D. Anderson, Lukasz L. Stelinski, et al.treatment according to the manufacturer’s instructions. Purified total RNA was quantified using a DeNovix DS-11 FX spectrophotometer (DeNovix Inc., Wilmington, DE, USA). For digital PCR, reactions were prepared using

(14) A lipid nanoparticle-based mRNA vaccine elicits immunity against porcine circovirus type 2 in miceMicrobiology SpectrumApril 7, 2026Jiaqi Nie, Chongyu Tian, He Huang, Jiahan Gang, Yue Chen, Mingshuo Ji, Jixiang Sun, Yongfei Zhou, Liming Liu, Wanbo Taiwere characterized using dynamic light scattering on a Zetasizer Nano ZS instrument (Denovix, Model: DS-11). Additionally, morphological attributes and structural integrity of the LNPs were visualized by transmission electron microscopy

(15) Rapid and repeated evolution of myosin copy number in threespine sticklebackCurrent BiologyApril 6, 2026Alyssa M. Yoxsimer, Rhea R. Daugherty, Emily E. Hare, Yingguang Frank Chan, Felicity C. Jones, Garrett A. Roberts Roberts Kingman, Emma G. Offenberg, Timothy R. Howes, Haili Zhang, Alex A. Pollen, et al.Center. At all steps, quantification was performed with Qubit dsDNA HS (Invitrogen, Q32854) measured on DS-11 FX (Denovix) and size distribution checked using FEMTO Pulse (Agilent, M5330AA & FP-1002-0275). HMW DNA

(16) circFKBP8(5S,6)-encoded protein modulates α-synuclein expression in SH-SY5Y cellsMol Biol RepApril 2, 2026Jude Uzoechina, Zhijun ZhangLtd., China) according to the manufacturer’s instructions, and purity was assessed using a DeNovix DS-11 Nanodrop spectrophotometer. After RNA extraction from cells and examination of RNA purity, RNA was reverse-transcribed

(17) Ginsenosides Rb3 and Rc Exhibit Anti-Amoebic Activities Against Naegleria fowleri, the Etiological Agent of Primary Amoebic MeningoencephalitisPharmaceuticals (Basel)April 2, 2026Thu Hằng Nguyễn, Hương Giang Lê, Tuấn Cường Võ, Minkyoung Cho, Byoung-Kuk NaGermany). RNA concentration of each sample was measured using a Nanodrop spectrophotometer (DeNovix DS-11; Wilmington, DE, USA) and then equalized. RNA was transcribed into complementary DNA (cDNA) using the

(18) Engineered prebiotic microcapsules Co-Encapsulating berberine and curcumin Elicit multi-synergistic therapy for ulcerative colitisMaterials Today BioApril 1, 2026Huanyu Li, Chuanyu Zhang, Ziwei Yang, Yifan Li, Dan Liu, Yanan Zhang, Lingmin Zhang, Ning Wang, Mingxin Zhang, Mingzhen Zhang, et al.g for 2 min, and the supernatant was transferred. RNA yield and quality were checked via Nanodrop (DS-11FX+, DeNovix). Total RNA was reverse-transcribed to cDNA using BeyoRTⅢ Premix and GDNA EZeraser (Beyotime).

(19) Ozone Treatment Attenuates Neuroinflammation and Alters miRNA Expression in a Rat Model of Post-Traumatic EpilepsyNeurochemical ResearchApril 1, 2026Hüseyin Demir, Cumaali Demirtas, Hava Yildirim, Ecem Demir, Sezin Kiroglu Uzun, Kubra Sevgin, Hakan Beyaztaş, Eray Metin Güler, Gulam Hekimoglu, Ender Mehmet Coskunpinar, et al.Germany). RNA purity and concentration were assessed spectrophotometrically at A260/A280 with a DENOVIX DS-11 FX. cDNA was synthesized using the miRCURY LNA RT Kit (Qiagen). All reagents were kept at − 20 °C and RNA

(20) Recovering Historical eDNA From Museum-Preserved Filter Feeders via Non-Destructive MetabarcodingMol Ecol ResourMarch 30, 2026Gert-Jan Jeunen, Sadie Mills, Marc Bailie, Quentin Mauvisseau, Miles Lamare, Stefano Mariani, William Pearman, Monika Zavodna, Jackson Treece, Sara Ferreira, et al.measured on Qubit Flex (Cat # Q32854; Qubit dsDNA HS Assay Kit, ThermoFisher Scientific, US) and Denovix DS‐11 FX+ (Cat # 30266629; Denovix, US). Library preparation followed the protocol of (Jeunen, Mills, et al.

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(1)

4/1/2019Spectrophotometer for Precise and Reliable Measurements - DeNovix Mriganka RayThis spectrophotometer is an easy-to-use, compact instrument and delivers full-spectrum UV-Vis analysis and fluorescence capability. It is a great instrument for rapid nucleic acid and protein ... Read Review
(1)

2/27/2019A Must-Use Instrument for Sequencing Library Preparation Shashikumar SuryaThis equipment is one of my favourite instruments for sequencing library preparation, in each step required to know the DNA quantity and quality throughout the library preparation, it's pretty ... Read Review
(1)

2/6/2018Well Designed and Thought Through Spectrophotometer Lada SychevaWe used this instrument a lot in the process of production of different proteins to make vaccines. Quick measurement of DNA and protein concentrations using small volume samples was instrumental for ... Read Review
(1)

12/29/2017Simple to Use Spectrophotometer Franziska IrmerThe DS-11 is easy to use for my students and me. It requires no additional chemicals or waiting times.
(1)

11/17/2016A Modern And Convenient Multi-Purpose Instrument Amra SaricWe are very happy with our DeNovix Spectrophotometer/Fluorometer. The instrument has multiple capabilities: can measure DNA, RNA and protein via microvolume, cuvette and test tube methods. Not to ... Read Review
(1)

12/8/2015DeNovix DS-11 Spectrophotometer Nancy HernandezIn our lab we perform a lot of molecular biology and protein expressions. The DS-11 spectrophotometer is really great for measuring DNA/RNA/ and protein concentrations. The fact that it has an easy to... Read Review
(1)

7/16/2015The DeNovix DS-11 Spectrophotometer I TOur group does a lot of cloning using restriction enzymes. Typically, we have small volumes of the materials along with low quantities after purification of the digested vector and insert by agarose ... Read Review

Sample Quantity and Quality Control for Next-Gen Sequencing
June 27, 2017
Robust procedures for sample input are essential to ensure consistent results through the workflow. read more
Five Ways to Improve the Accuracy of 1-Microliter UV-Vis Quantification
March 30, 2015
The ability to measure microliter volumes of samples via UV-visible (UV-vis) spectrophotometry has launched a revolution in molecular-biology labs in the last decade. Understanding best practice for preparing and ... read more

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DS-11 Series Spectrophotometer / Fluorometer from DeNovix Inc.

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DeNovix Inc.

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Bench Tips

Sample Quantity and Quality Control for Next-Gen Sequencing

Five Ways to Improve the Accuracy of 1-Microliter UV-Vis Quantification

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