AKT, also known as Protein Kinase B, is a serine/threonine kinase that has been shown to be involved in a wide range of cellular processes including cell signaling, proliferation and migration, metabolism and apoptosis among others. Because of its potential role in a number of cancers, inhibitors to AKT family members (which includes AKT 1, 2 and 3) are being actively pursued by many pharmaceutical companies as potential therapeutic agents. There are, however, a number of small molecule inhibitors of AKT family members that are well characterized and can be used in laboratory settings. Some of these inhibitors are specific to particular AKT family members while others block all of them. The working concentrations for these inhibitors cover a broad range depending on the assay being used as well as the sample types, etc. Compare specific AKT inhibitors side by side below.