The Biocompare Inhibitor Search Tool lets researchers browse thousands of compounds by searching by inhibitor name or by its target enzyme. Simply search by “Keywords” if you know the name of the inhibitor, or search by “Inhibitor Target” to enter the name of your protein of interest. Additionally, you may check the appropriate boxes to narrow down your search.
Caspase-8 is a cysteine protease known for its roles in Fas-induced apoptosis and lymphocyte activation. Activation of caspase-8 is an initiator for several other members of the caspase family and can lead to downstream mitochondrial damage. Caspase-8 inhibitors are being explored for their potential therapeutic roles in neurodegenerative diseases and cancer. Compare caspase-8 inhibitor listings below.